Peer Review History

Original SubmissionSeptember 22, 2025
Decision Letter - Andrej Kielbassa, Editor

Dear Dr. Varmazyari,

Thank you for submitting your manuscript to PLOS ONE. After having commented on your submission (please see our comments given below), and after careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Jan 12 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org . When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.
  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.
  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols . Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols .

We look forward to receiving your revised manuscript.

Kind regards,

Andrej M Kielbassa

Academic Editor

PLOS ONE

Journal requirements:

When submitting your revision, we need you to address these additional requirements.

1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at

https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and

https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf

2. In the ethics statement in the Methods, you have specified that verbal consent was obtained. Please provide additional details regarding how this consent was documented and witnessed, and state whether this was approved by the IRB.

3. Thank you for stating the following financial disclosure:

“This study was supported in part by funding from Tehran University of Medical Sciences as a student thesis grant.”

Please state what role the funders took in the study.  If the funders had no role, please state: "The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."

If this statement is not correct you must amend it as needed.

Please include this amended Role of Funder statement in your cover letter; we will change the online submission form on your behalf.

4. We are unable to open your Supporting Information file [S2 File.sav]. Please kindly revise as necessary and re-upload.

If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: No

Reviewer #2: Yes

**********

2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #1: No

Reviewer #2: Yes

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: Yes

**********

Reviewer #1: This submitted draft would seem interesting, is considered easily intelligible, and might be worth following after some revisions and clarifications.

Title

- Please add type of study.

Abstract

- Please stick to Journal style.

- Please revise for uniform Journal style, see "p = 0.040".

- When it comes to your conclusions, please exclusively stick to your aims. Remember that you wanted To "explore parents’ perceptions of Iran’s SOHPP, the sociodemographic factors shaping them, and children’s post-program oral health behaviors". Do not simply repeat your results here. Do not speculate. Do not provide well-accepted (but meaningless) phrases. Instead, provide a reasonable and generalizable extension of your outcome.

Intro

- More than two full pages would not be adequate for such a study, Please simply elaborate both aims and objectives, and present a sound rationale. A one-page Intro would seem adequate.

- Please adapt your reference style, and use square brackets. "(...) of school-aged children worldwide (1, 2)." must read "(...) of school-aged children worldwide [1, 2]." Revise thoroughly.

- At the end of this section, please remember that you have statistically analyzed your data, so, consequently, a sound null hypothesis must be presented. The latter must be deducible from the foregoing thoughts.

Meths

- Please remember that Plos One will consider publishing qualitative research only if it adheres to appropriate study design and reporting guidelines, as described in the submission guidelines. For example, "qualitative data sources include, but are not limited to, interviews, (...), and free-form answers to questionnaires and surveys". For more information, please go to https://journals.plos.org/plosone/s/submission-guidelines#loc-qualitative-research. You have submitted the outcome of "phone-surveyed parents of primary school children", and such a study might be semi-quantitative, or even qualitative. Please clarify.

- Additionally, please go to https://journals.sagepub.com/doi/10.1177/1049732315617444, and discuss your set-up with reference to your sample size.

- With this section your define your study as being "cross-sectional". You surely will know that cross-sectional studies are a type of observational studies. The latter must be pre-registered, please see https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2836842. Please provide you a-priori registration date and number.

- Your sample size calculation would not seem clear. Please provide more details. See comments given above.

- With your calculated sample size being 347, why did you approach "525 individuals"? Please clarify.

- Same with " Four centers, Ayat, Farmafarmanian, Imam Hassan Mojtaba, and Avicenna, were randomly selected from this list." Please clarify your randomization approach.

- Note that with ALL materials and methodologies (including statistical software), please use general/non-proprietary names with your text, followed by (brand name; manufacturer, city, ST[ate - abbreviated, if US], country) in parentheses. Stick to semicolon. Revise thoroughly.

Results

- Again, compare "p = 0.040", "p = .011", "p = 0.040" and "P-value". Revise for uniform Journal style. Consulting some recently published Plos One papers should be helpful.

Disc

- Stick to H0 when starting this section.

- Do not provide a literature review here. This section will benefit from a sound DISCUSSION.

Concl

- This section would not seem satisfying. Remember that "Conclusions" does not mean "Summary" (or "Repetition of Outcome"). Revise carefully.

- Again, with your Conclusions, please stick exclusively to your aims. Do not simply repeat your results here. Do not speculate. Do not provide well-accepted (but meaningless) phrases. Instead, provide a reasonable and generalizable extension of your outcome.

Refs

- Your references list must be adapted to Journal style. Remember that this is considered your task, to avoid any mistakes.

In total, several shortcomings and drawbacks do not allow for any proceeding with this draft, and re-review is considered mandatory.

Reviewer #2: The study employed a cross-sectional analytical design, which is well suited to exploring parents’ perceptions, awareness, and satisfaction with the Students’ Oral Health Promotion Program (SOHPP). Sampling was carried out across four randomly selected comprehensive healthcare centers, yielding a 67% response rate and a total of 354 participants—an adequate and reasonably representative sample. The questionnaire was carefully developed and underwent simplified validation through assessments of face and content validity, along with test–retest reliability, which is appropriate considering the descriptive focus of the measures. Statistical analyses, including ANOVA, chi-square tests, and regression models with backward elimination, were appropriate for the study objectives. The authors verified assumptions such as multicollinearity and model fit, which were found to be acceptable. Ethical approval was obtained from the relevant institutional review board, and informed consent procedures were clearly described and properly implemented.

The study’s main findings—high levels of parental awareness and satisfaction, notable sociodemographic differences (particularly related to fathers’ education and occupation), and the presence of a perception–behavior gap—are clearly supported by both the descriptive and inferential data. The interpretation of results is balanced, recognizing the strengths of the program as well as its limitations, including the cross-sectional design, reliance on self-reported information, and limited generalizability. The conclusions are consistent with the evidence presented and appropriately emphasize the need to strengthen treatment-related elements, improve communication, and adapt outreach efforts to different parental backgrounds.

Comments to the Authors

The introduction could be strengthened by more clearly outlining why parents’ perspectives are critical for the long-term success and sustainability of school-based oral health programs. It would also help to clarify how this study addresses existing gaps in the regional or international literature.

Regarding questionnaire validation, the manuscript mentions face and content validity and a test–retest approach. Including additional information—such as the time interval between tests or any calculated reliability values—would make the instrument’s credibility clearer.

Because the awareness and satisfaction indices were based on only a few items, it might be worth acknowledging this as a methodological limitation. You could suggest that future studies use a more detailed psychometric assessment, such as reliability testing or factor analysis, to improve measurement precision.

The statistical approach is well chosen and explained. However, the use of backward regression could be better justified. A brief explanation of why this method was selected, and whether sensitivity analyses were done to confirm model stability, would enhance transparency.

The discussion is well developed and connects effectively with previous research. Still, the paper would benefit from a stronger emphasis on practical implications—particularly how the observed links between fathers’ education, government employment, and program perceptions could guide the design of future oral health interventions or communication strategies.

**********

what does this mean? ). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy

Reviewer #1: No

Reviewer #2: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

To ensure your figures meet our technical requirements, please review our figure guidelines: https://journals.plos.org/plosone/s/figures

You may also use PLOS’s free figure tool, NAAS, to help you prepare publication quality figures: https://journals.plos.org/plosone/s/figures#loc-tools-for-figure-preparation.

NAAS will assess whether your figures meet our technical requirements by comparing each figure against our figure specifications.

Revision 1

The response to reviewers file is attached.

Attachments
Attachment
Submitted filename: Point-by-point Response.docx
Decision Letter - Andrej Kielbassa, Editor

Parents’ perspectives on a national child oral health promotion program: sociodemographic influences and behavioral insights – a cross-sectional analysis

PONE-D-25-51769R1

Dear Dr. Varmazyari,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

An invoice will be generated when your article is formally accepted. Please note, if your institution has a publishing partnership with PLOS and your article meets the relevant criteria, all or part of your publication costs will be covered. Please make sure your user information is up-to-date by logging into Editorial Manager at Editorial Manager®  and clicking the ‘Update My Information' link at the top of the page. For questions related to billing, please contact billing support .

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Prof. Dr. Dr. h. c.Andrej M Kielbassa

Academic Editor

PLOS One

Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #1: All comments have been addressed

Reviewer #2: All comments have been addressed

**********

2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #1: Yes

Reviewer #2: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: Yes

**********

Reviewer #1: With the help of the reviewers, this revised and re-submitted draft has been considerably improved. Still, there would seem minor typos, and, unfortunately, the references again have not been adapted to uniform Journal style. These shortcomings might be handled together with the typesetter.

Reviewer #2: The revised manuscript satisfactorily addresses the points raised in the initial review. The study design is now clearly stated, the abstract and references follow journal style, and the introduction has been streamlined with the addition of an explicit null hypothesis. The authors also clarify the quantitative nature of the study, provide clearer explanations of the sample size calculation, recruitment strategy, and random selection of centers, and ensure consistent reporting of statistical results.

Overall, the manuscript is clearer and more transparent. Methodological details, data availability, and ethical procedures are adequately documented, the discussion is more focused on interpretation, and the conclusions are aligned with the study aims rather than repeating results. I confirm that the issues raised previously have been addressed in the revised version, which now meets the criteria for publication in PLOS ONE.

**********

what does this mean? ). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy

Reviewer #1: No

Reviewer #2: No

**********

Formally Accepted
Acceptance Letter - Andrej Kielbassa, Editor

PONE-D-25-51769R1

PLOS One

Dear Dr. Varmazyari,

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS One. Congratulations! Your manuscript is now being handed over to our production team.

At this stage, our production department will prepare your paper for publication. This includes ensuring the following:

* All references, tables, and figures are properly cited

* All relevant supporting information is included in the manuscript submission,

* There are no issues that prevent the paper from being properly typeset

You will receive further instructions from the production team, including instructions on how to review your proof when it is ready. Please keep in mind that we are working through a large volume of accepted articles, so please give us a few days to review your paper and let you know the next and final steps.

Lastly, if your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

You will receive an invoice from PLOS for your publication fee after your manuscript has reached the completed accept phase. If you receive an email requesting payment before acceptance or for any other service, this may be a phishing scheme. Learn how to identify phishing emails and protect your accounts at https://explore.plos.org/phishing.

If we can help with anything else, please email us at customercare@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Prof. Dr. med. dent. Dr. h. c. Andrej M Kielbassa

Academic Editor

PLOS One

Open letter on the publication of peer review reports

PLOS recognizes the benefits of transparency in the peer review process. Therefore, we enable the publication of all of the content of peer review and author responses alongside final, published articles. Reviewers remain anonymous, unless they choose to reveal their names.

We encourage other journals to join us in this initiative. We hope that our action inspires the community, including researchers, research funders, and research institutions, to recognize the benefits of published peer review reports for all parts of the research system.

Learn more at ASAPbio .