Dear Dr. Mukdadi,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

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We look forward to receiving your revised manuscript.

Kind regards,

Orion Haas Junior, DDS, OMFS, MSc, PhD

Academic Editor

PLOS ONE

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Additional Editor Comments:

The reviewers asked some revision.

You should follow all the recommendations for a future acceptance

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: Yes

Reviewer #2: Yes

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2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

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3. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #1: Yes

Reviewer #2: Yes

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4. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1:  Thanks for your nice work , i appreciate it, i would suggest if you publish another article later with pre and post accompanied with patients photos, and with CBCT imaging to show the effect of ATOZ expander more clearly. By anyway thanks for your hard work.

Reviewer #2:  • Both the quality and data presentation of this manuscript are acceptable and of great importance to Maxillofacial surgeon, ENT surgeon, and Orthodontist.

• The manuscript expands our knowledge about the facial expansion and orthodontics.

• The title should be re-write to be more precise & informative.

• The abstract should more informative and should be reflect the content of the article and must be with range of 250 words.

• Four –six keywords should be place not mentioned in title but reflect the manuscript.

• Few more paragraphs should be incorporated to introduction about other studies in diagnosis and management of other causes including congenital and trauma in pediatric age group.

Suggested References:

Aldelaimi TN. New maneuver for fixation of pediatric nasal bone fracture. J Craniofac Surg. 2011;22(4):1476-1478. doi:10.1097/SCS.0b013e31821d1997.

Srivastava D, Singh H, Mishra S, Sharma P, Kapoor P, Chandra L. Facial asymmetry revisited: Part I- diagnosis and treatment planning. J Oral Biol Craniofac Res. 2018;8(1):7-14. doi:10.1016/j.jobcr.2017.04.010

Aldelaimi TN, Khalil AA. Surgical management of pediatric mandibular trauma. J Craniofac Surg. 2013;24(3):785-787. doi:10.1097/SCS.0b013e31828b6c47

• Increase resolution and contrast for each figure within the manuscript with .

• Arrows should be place to each pictures for illustration.

• The author( s) should pay attention to writing and typing errors

• The statements in text are acceptable but more paragraphs about the justification of your findings and comparison with other relevant studies.

• Up to date references should be added to reference list and the old should be omitted.

Good Luck

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Reviewer #1: Yes:  Ahmed Abouelnour

Reviewer #2: Yes:  Tahrir Aldelaimi

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Finite Element Modeling of Asymmetric Expansion using ATOZTM Expander

PONE-D-25-06726R1

Dear Dr. Ouldyerou,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Orion Haas Junior, DDS, OMFS, MSc, PhD

Academic Editor

PLOS ONE