PONE-D-24-16957Effectiveness of Interventions for Preventing Road Traffic Injuries: A Systematic Review in Low-, Middle- and High-income CountriesPLOS ONE

Dear Dr. Bagheri Lankarani,

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Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

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Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

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3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

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4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: The article focuses on a pilot study conducted in Lebanon, which may limit the generalizability of the findings to other countries or regions with different agricultural practices, literacy rates, and cultural contexts.

1- The article does not provide details on the sample size used for the pilot study. A larger sample may be needed to ensure the robustness of the validation process and the reliability of the questionnaire.

2- The article does not provide detailed information on the demographic characteristics of the participating farmers, such as age, education level, farming experience, and socioeconomic status. These factors may influence the understanding and practices related to pesticide labels.

3-The item reduction and development of the questionnaire relied on the evaluation and recommendations of a panel of five experts. This process could be subject to individual biases and perspectives, potentially influencing the content and structure of the final questionnaire.

4-The article does not mention any cross-validation of the questionnaire with a separate sample or population. Cross-validation would help assess the stability and generalizability of the questionnaire's psychometric properties.

5- The article focuses on the development and validation of the questionnaire, but does not provide insights into the practical application of the tool in real-world settings or its impact on improving farmers' understanding and practices related to pesticide labels.

6- The article does not specify the time frame of the data collection, which may limit the relevance of the findings if the study was conducted some time ago and agricultural practices or labeling regulations have since changed.

7- The article does not compare the newly developed questionnaire to other existing tools for assessing pesticide label comprehension and practices, which could help establish its added value or unique features.

Reviewer #2: Overall the analysis was done in multi-dimensional angle and info graph were well presented. Few typos were found in the background and figure caption. My other comments were uploaded as an attachment.

Reviewer #3: This paper attempts to provide a review of past studies investigating the effectiveness of interventions for preventing traffic injuries in low, middle and high income countries. The following issues need to be clarified before this reviewer has a favourable recommendation.

1. The review is not specific to children injuries. The mention of children injuries in BACKGROUND of Abstract is not needed. Please consider removing it.

2. The focuses of this review are broad. While drink driving and restraint use have been the focuses of traffic intervention points in developed countries, other issues such as infrastructures, or perhaps helmet use, might be the focus in developing countries. Comparing the effectiveness of intervention points among developing/developed countries is probably not proper.

3. Please clarify why a traditional meta analysis was not conducted.

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Reviewer #1: No

Reviewer #2: No

Reviewer #3: No

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Attachments

Attachment

Submitted filename: Review comments_RTI.docx

Effectiveness of Interventions for Preventing Road Traffic Injuries: A Systematic Review in Low-, Middle- and High-income Countries

PONE-D-24-16957R1

Dear Dr. Lankarani,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Kind regards,

Rayan Jafnan Alharbi, Ph.D

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #2: All comments have been addressed

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2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #2: Yes

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3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #2: Yes

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4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #2: Yes

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5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #2: Yes

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6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #2: All comments are accurately addressed. the objectives were revised, search engines names were added and other feedback was also incorporated. Best wishes to author.

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7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #2: Yes: Nawshin Torsha

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Attachments

Attachment

Submitted filename: Authors Response To Reviewer Comments.pdf