PONE-D-24-25387Factors Associated with Uptake of Human Papilloma virus Vaccine among Adolescent girls: A cross sectional survey on insights into HPV Infection Prevention in Kabarole District -Western UgandaPLOS ONE

Dear Dr. Mugisa,

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PLOS ONE

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Reviewers' comments:

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Reviewer #1: Partly

Reviewer #2: Partly

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: N/A

Reviewer #2: No

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Reviewer #1: No

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: No

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Reviewer #1: Very Respected Authors,

After carefully reading your paper I have few suggestions. Keywords are usually listed below the abstract. The objective of the study is clear. It is necessary to specify the methodology. Between December 18/10/2021 to 18/10/2022 we conducted a A cross-sectional study design line 21. I do not understand. I see that the study was done in October. Could you please, explain the sample size and the exact timing of when the study was conducted? The date of the Ethics Committee's decision and its reference number are required lines 103-105.

Reviewer #2: The research talks about a very important and topical issue especially in the aspect of elimination of cervical cancer.

But I have some major concerns with the manuscript

1. Data analysis: The values of the AOR 4.06 does not fall within the CI of (0.69-0.087), also OR of 0.4 does not fall within the CI of (1.43-8.09) all this are written under the abstract.

2. Under the results section: Even though the AOR and OR seem to fall within the CI but now it makes the whole results inconsistent. Kindly address that, because this ultimately affects interpretation and discussion of results.

3. The references are not serially numbered example under introduction from number 1, the next reference was (42), and it also seem to be inconsistent having a mix of both APA and Vancouver styles. Please address that.

4. Data collection: what's the rationale of using 10 for pretesting.

4. Other minor issues include the typographical errors.

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Reviewer #1: No

Reviewer #2: Yes:  Maryam Jamila Ali

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Factors Associated with Uptake of Human Papilloma virus Vaccine among Adolescent girls: A cross sectional survey on insights into HPV Infection Prevention in Kabarole District -Western Uganda

PONE-D-24-25387R1

Dear Dr. Mugisa,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Kind regards,

Jonah Musa, MBBS, MSCI,PhD

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments: