Peer Review History

Original SubmissionJuly 22, 2023
Decision Letter - Giovanni Tossetta, Editor

PONE-D-23-23164The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse modelPLOS ONE

Dear Dr. Wong,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

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Kind regards,

Giovanni Tossetta, Ph.D

Academic Editor

PLOS ONE

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: I Don't Know

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3. Have the authors made all data underlying the findings in their manuscript fully available?

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Reviewer #1: Yes

Reviewer #2: Yes

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4. Is the manuscript presented in an intelligible fashion and written in standard English?

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Reviewer #1: Yes

Reviewer #2: Yes

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5. Review Comments to the Author

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Reviewer #1: Aferre thoroughly reading the paper, twice, I found no reason for demanding changes nor corrections of the text . Perhaps it could be summarised a little bit as it is rather long. This notwithstanding I recommend to publish it in its current form

Reviewer #2: I read this manuscript and found it very interesting especially nowadays with the prevalence of overweight and obesity.

I have some advice regarding citing many statements both in the introduction and in the discussion .

Many statements need appropriate citing.

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Reviewer #1: Yes: Juan Carlos BELLO MUÑOZ

Reviewer #2: Yes: Naser Al-Husban

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Revision 1

RESPONSE TO REVIEWERS

REVIEWER 1:

After thoroughly reading the paper, twice, I found no reason for demanding changes nor corrections of the text. Perhaps it could be summarised a little bit as it is rather long. This notwithstanding I recommend to publish it in its current form

We thank the Reviewer for the positive comments!

REVIEWER 2:

I read this manuscript and found it very interesting especially nowadays with the prevalence of overweight and obesity. I have some advice regarding citing many statements both in the introduction and in the discussion. Many statements need appropriate citing.

We thank the Reviewer for the positive review. We have now included 8 additional citations (ref #’s 5, 6, 7, 8, 23, 44, 53, and 60) and cited #’s 45, 46 [old #’s 40 and 41] for another statement) in the Introduction and Discussion as recommended.

Attachments
Attachment
Submitted filename: Responses_to_Reviewers.docx
Decision Letter - Giovanni Tossetta, Editor

The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model

PONE-D-23-23164R1

Dear Dr. Wong,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Giovanni Tossetta, Ph.D

Academic Editor

PLOS ONE

Formally Accepted
Acceptance Letter - Giovanni Tossetta, Editor

PONE-D-23-23164R1

The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model

Dear Dr. Wong:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Giovanni Tossetta

Academic Editor

PLOS ONE

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