Peer Review History

Original SubmissionNovember 16, 2022
Decision Letter - Nosheen Nasir, Editor

PONE-D-22-31633The effect of diabetes mellitus on COVID-19 mortality among patients in a tertiary-level hospital in Bandung, IndonesiaPLOS ONE

Dear Dr. Koesoemadinata,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

==============================Please describe how your study differs from others which have shown same association between Diabetes and COVID-19? State the strengths and limitations of your study in the discussion draft.==============================

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We look forward to receiving your revised manuscript.

Kind regards,

Nosheen Nasir

Academic Editor

PLOS ONE

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Additional Editor Comments:

Please describe how your study differs from what is already reported about this association?

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

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Reviewer #1: Yes

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Reviewer #1: Yes

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Reviewer #1: The review was well written, clear, precise and to the point. The authors provided clear figures with legends, and overall the manuscript was easy to follow and understand. The discussion was elaborately done and overall, this was a good job.

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Reviewer #1: No

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Revision 1

Manuscript ID PONE-D-22-31633

The effect of diabetes mellitus on COVID-19 mortality among patients in a tertiary-level hospital in Bandung, Indonesia

Dear Prof. Nosheen Nasir and Reviewers,

Thank you for the helpful comments on our manuscript. We have now addressed the issue raised and edited the manuscript accordingly.

Editor comments:

Please describe how your study differs from what is already reported about this association. State the strengths and limitations of your study in the discussion draft.

We acknowledge that other studies have investigated the association between diabetes mellitus (DM) and COVID-19 outcomes. However, there are additional strengths of our research besides this association. We added, “Compared to other studies investigating the association between DM and COVID-19 outcomes, this study provides more descriptive information about the laboratory characteristics of COVID-19 patients with DM in Indonesia, which could offer important knowledge for clinicians, especially for treatment considerations. Our study also only included patients with rRT-PCR results to minimize misclassification bias. Moreover, the sample size of our study is relatively large.” (Lines 275-280).

We also added, “Our study has limitations; firstly, the data used in this study were retrieved during the first COVID-19 wave in Indonesia. Therefore, even though it gives valuable insight into how DM affects COVID-19 patients, vaccination and the spread of infection later may change the clinical characteristics of COVID-19 patients with DM. Secondly, ...” (Lines 282-285).

Journal requirements:

1. Please ensure that your manuscript meets PLOS ONE’s style requirements, including those for file naming.

We have ensured that our manuscript meets the requirements.

2. In your Data Availability statement, you have not specified where the minimal data set underlying the results described in your manuscript can be found. PLOS defines a study’s minimal data set as the underlying data used to reach the conclusions drawn in the manuscript and any additional data required to replicate the reported study findings in their entirety. All PLOS journals require that the minimal data set be made fully available.

We have uploaded the minimal data set as a Supporting Information file.

The feedback is highly valuable, and we are grateful for your constructive input on our manuscript. Considering the raised concerns, we believe the paper has now improved.

On behalf of all authors,

Raspati Cundarani Koesoemadinata, MD, MSc

Research Center for Care and Control of Infectious Disease

Universitas Padjadjaran, Bandung, Indonesia

Attachments
Attachment
Submitted filename: Response to Reviewers.docx
Decision Letter - Nosheen Nasir, Editor

The effect of diabetes mellitus on COVID-19 mortality among patients in a tertiary-level hospital in Bandung, Indonesia

PONE-D-22-31633R1

Dear Dr. Koesoemadinata,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Nosheen Nasir

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Formally Accepted
Acceptance Letter - Nosheen Nasir, Editor

PONE-D-22-31633R1

The effect of diabetes mellitus on COVID-19 mortality among patients in a tertiary-level hospital in Bandung, Indonesia

Dear Dr. Koesoemadinata:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

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Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Nosheen Nasir

Academic Editor

PLOS ONE

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