PONE-D-22-28224Risk of bias in prognostic models of hospital-induced delirium for medical-surgical units: A systematic reviewPLOS ONE

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: The manuscripts was well written with just minor correction "Every year delirium complicates hospital stays for greater than 2.3 million adults of 65 years", The number of events, i.e., the smaller (should be the small) of the number of participants with the outcome and the number of participants without the outcome,[35].

I would like for the authors to elaborate on the consensus? The consensus technique employed, is it a Delphi technique? and the consensus reached by the two independent reviewer was two, a references to this should be stated to support that two independent reviewer can be used to reach a consensus.

Reviewer #2: The authors have carried out an interesting systematic review of hospital induced delirium in medical and surgical wards comprising patients managed by the medical and surgical units.

This study appropriately followed the standard process of a systematic review manuscript and the methodology and results were appropriately selected. The conclusion is in tandem with the evidence provided from the study.

ln page 9, General surgical hospitals have both medical and surgical patients wards, l am a little worried how those patients in the General Hospital wards that might have both medical and surgical patients were also excluded from the study?

ln page 15, understand the review of the articles were those written in English, what efforts were made to get appropriate English language translational application to get some of the excluded journal articles that were excluded in the study please?

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Reviewer #1: Yes: Chigozie Gloria Anene-Okeke

Reviewer #2: No

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Submitted filename: PONE-D-22-28224.pdf

Risk of bias in prognostic models of hospital-induced delirium for medical-surgical units: A systematic review

PONE-D-22-28224R1

Dear Dr. Snigurska,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Kind regards,

Blessing Onyinye Ukoha-kalu, Ph.D

Guest Editor

PLOS ONE

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