PONE-D-22-27844Fatigue And Associated Factors Among Adult Cancer Patients Receiving Cancer Treatment At Oncology Unit In Amhara Region, Ethiopia, 2022PLOS ONE

Dear Dr. Dejen Tsegaye,

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Reviewer #1: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

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Reviewer #1: Yes

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Reviewer #1: Yes

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5. Review Comments to the Author

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Reviewer #1: The topic is interesting discussing the prevalence of cancer related fatigue, a common symptom in cancer patients that is usually ignored and underestimated. Fatigue can significantly affect the patients’ quality of life.

General

• The article requires language editing.

Title:

• Appropriate and descriptive but I would prefer that the year should be removed from the title.

Abstract:

• “Fatigue among cancer”: I think it should be fatigue among cancer patients. kindly revise

• Results: with non-response rate of 9: what is the number 9? The rate is usually not a crude number it should be related to denominator as 9% or 9/1000 patients .

• Line 3 in the results: “physical inactive “ should be replaced with physical inactivity

• Kindly remove redundancy. The conclusion includes repetition of the results.

Introduction:

• Well written and descriptive.

Material and methods:

• Line 67: I think study area should be replaced with setting

• Population: the authors should simply mention that the eligible criteria is cancer patients receiving treatment. kindly remove redundancy.

• Line 84: “and” should be added before hearing or intellectually impaired

• Table 1 is not cited in text.

• It is not clear why the sample size was multiplied by 1.5.

• Sapling procedure is not clear. why stratified sampling was used ? what is the factor used for stratification?

• Operational definition: it would be better if summarized in a table

• How were all these questionnaires filled? Was that by face-to-face interview? How long did it take from each patient to film all these questions?

Results:

• Line 313: on why p-values was <0.25. selected to select variable?

• Line 334: it should be table 4 and should be cited in text.

• All data mentioned from line 319 to 333 are repeated in the table. Please remove unnecessary repetitions.

• Figures are not cited in text.

• Figures numbering is not correct

Discussion:

• Well written.

• The authors did not mention the limitations of their study.

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Reviewer #1: No

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Fatigue And Associated Factors Among Adult Cancer Patients Receiving Cancer Treatment At Oncology Unit In Amhara Region, Ethiopia, 2022

PONE-D-22-27844R1

Dear Dejen Tsegaye

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Muhammad Junaid Farrukh

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments: