Incidence and risk of periodontitis in obstructive sleep apnea: A meta-analysis

Zhiqiang Zhang; Sitong Ge; Guanhong Zhai; Sihan Yu; Zhezhu Cui; Shurui Si; Xiang Chou

doi:10.1371/journal.pone.0271738

Peer Review History

Original SubmissionApril 5, 2022
15 Jun 2022 Decision Letter - Federica Provini, Editor PONE-D-22-09585Incidence and risk of periodontitis in obstructive sleep apnea:a meta-analysisPLOS ONE Dear Dr. Cui, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Jul 25 2022 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file. 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The PLOS ONE style templates can be found at https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. Reviewer #1: Yes ******** 2. Has the statistical analysis been performed appropriately and rigorously? Reviewer #1: Yes ****** 3. Have the authors made all data underlying the findings in their manuscript fully available? The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified. Reviewer #1: Yes ****** 4. Is the manuscript presented in an intelligible fashion and written in standard English? PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here. Reviewer #1: Yes ****** 5. Review Comments to the Author Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters) Reviewer #1: The study presents a current and relevant theme. I suggest the following revisions. In the Abstract, Introduction, I think the aim of the study was to carry out a systematic review with meta-analysis on the association between OSA and periodontitis. I suggest that the authors rewrite this Abstract topic. In the Introduction of the manuscript, the theme is well founded. However, I propose that the association between gingival dryness in patients who snore and/or present OSA be reported, which may trigger periodontal problems. There are studies that report this association. I think this description helps to substantiate the possible association between periodontitis and OSA. Methodology: The methodology is very well described. I propose that authors present the elaborate search key. Discussion: This topic is very well described. I suggest that the authors discuss the fact that most of the selected studies in this manuscript, belonged to the Asian continent. Why has the Asian continent studied this topic more? I think it's important to discuss. ****** 6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy. Reviewer #1: Yes:** Junia Maria Serra-Negra [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.] While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step. https://doi.org/10.1371/journal.pone.0271738.r001
Revision 1
21 Jun 2022 Author Response Response to editors’ and reviewers’ comments on the manuscript submitted by Zhang et al, “Incidence and risk of periodontitis in obstructive sleep apnea: a meta-analysis”. (Manuscript ID: PONE-D-22-09585) We appreciate the editors and reviewers for their constructive and valuable comments. We have revised our manuscript according to the editors’ and reviewers’ comments, questions, and suggestions. In the event that we missed any one of the comments please let us know. This document includes our responses to editors’ and reviewers’ comments point by point, and the revised portion are marked in RED color in our revision. Comments from Editor: Comment 1: Journal Requirements: When submitting your revision, we need you to address these additional requirements. 1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf Answer： Thank you for your kind and thoughtful advice. We have made detailed revisions and adjustments to the formatting of our manuscript in accordance with PLOS ONE's style requirements. Although we are very attentive, there may be some omissions or deficiencies, please let us know after reviewing, and we will spare no effort to improve. Comments from Reviewer Comment 1: The study presents a current and relevant theme. I suggest the following revisions. Answer：Thank you for the effort you put into our manuscript. We appreciate your constructive and valuable comments. We have revised our manuscript according to your comments point by point below. Comment 2: In the Abstract, Introduction, I think the aim of the study was to carry out a systematic review with meta-analysis on the association between OSA and periodontitis. I suggest that the authors rewrite this Abstract topic. Answer：Thank you for your inspiring comment. The topic of the Abstract has been rewritten as per your comment. See Page 2, Line 2~4. Change in text: The possible relationship between obstructive sleep apnea (OSA) and periodontitis is contradictory. Thus, the purpose of this study was to evaluate the association between OSA and periodontitis. Comment 3: In the Introduction of the manuscript, the theme is well founded. However, I propose that the association between gingival dryness in patients who snore and/or present OSA be reported, which may trigger periodontal problems. There are studies that report this association. I think this description helps to substantiate the possible association between periodontitis and OSA. Answer：Thank you for your great insight. Snoring and OSA can lead to gingival dryness, which in turn leads to periodontitis, which is also a common clinical phenomenon, so we deeply accept this view. We have further searched the literature to supplement and improve. See Page 4, Line 46~48. Change in text: In addition, gingival dryness, smoking, cardiovascular disease and genetic factors have also been confirmed to be related to the incidence of periodontitis [18-20]. Comment 4: Methodology: The methodology is very well described. I propose that authors present the elaborate search key. Answer：Thank you for your praise. Our detailed retrieval strategy is attached, which is to reduce the length and repeatability of the manuscript. Interested readers can download and view it. See S1 Table in Supplement. Comment 5: Discussion: This topic is very well described. I suggest that the authors discuss the fact that most of the selected studies in this manuscript, belonged to the Asian continent. Why has the Asian continent studied this topic more? I think it's important to discuss. Answer：Thank you for this interesting discovery. To be honest, we didn't realize that Asia had the most studies, if you hadn't reminded us. Under your reminder, we have carefully reviewed the included studies and tried to find a more comprehensive explanation. We tried to search the literature to prove this point, but failed to find a suitable one. Therefore, we raised this question in the limitations of this manuscript. See Page 15, Line 280~282. Change in text: In addition, the included studies focused more on Asian populations, and more research is needed to explore this association in populations of other continents. Attachments Attachment Submitted filename: Response letter.docx https://doi.org/10.1371/journal.pone.0271738.r002
7 Jul 2022 Decision Letter - Federica Provini, Editor Incidence and risk of periodontitis in obstructive sleep apnea:a meta-analysis PONE-D-22-09585R1 Dear Dr. Cui, We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements. An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org. If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org. Kind regards, Federica Provini Academic Editor PLOS ONE https://doi.org/10.1371/journal.pone.0271738.r003
Formally Accepted
12 Jul 2022 Acceptance Letter - Federica Provini, Editor PONE-D-22-09585R1 Incidence and risk of periodontitis in obstructive sleep apnea:a meta-analysis Dear Dr. Cui: I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department. If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org. If we can help with anything else, please email us at plosone@plos.org. Thank you for submitting your work to PLOS ONE and supporting open access. Kind regards, PLOS ONE Editorial Office Staff on behalf of Dr. Federica Provini Academic Editor PLOS ONE https://doi.org/10.1371/journal.pone.0271738.r004

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