PONE-D-21-19770Patient perspectives about mobile health to improve atrial fibrillation self-management and education: a mixed-methods study in SingaporePLOS ONE

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Reviewer #1: Partly

Reviewer #2: Partly

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: No

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: Yes

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5. Review Comments to the Author

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Reviewer #1: Dear Authors,

Please kindly consider the following suggestions for further improvement of the manuscript:

1. Title: To change the term 'mobile health' to the actual tool used i.e. SETAF

2. Methods: To include any specific info or features of SETAF that patients are required to explore during the 6-week duration. My concern is some patients may not explore at all or focus only 1-2 features that they like the most, given that there is a huge gap in the age of patients participated in this study. This is of course, unless, the researcher could remotely track all patients' use of SETAF throughout the duration.

3. Methods: To include a more detailed inclusion and exclusion criteria for the patients. For example, background educational level, familiarity with using smart phones and apps etc. This could potentially affect the results of this study.

4. Data analysis: To correct the completion rate of the self-management triage assessment. I noticed there is an overlap between the values i.e., 25-50% and 50-75%. The info in the table 3 is correct.

5. Data collection: To include the detail on whether or not a consent is obtained prior to the audio-recording.

6. Results: There were different N used in the results section. In Line 365, it was mentioned that 33 participated in the survey, and not 38 as mentioned in the earlier section. Please clarify.

Reviewer #2: Participants ages were stated by the author begins from 25 years old , while the

mean mean age was nearly 65 years old. This age issue represent an acceptable conflict as this high variation in participants ages implies different motivations to use mobile health . The validity and reliability of the used mobile health wasn't mentioned in the study . The author didn't mention how intra co- researcher variability was overcomed. Regarding to sample size calculation was not mentioned , however sample size was small. statistical method was unclear and not obviously mentioned.

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Reviewer #1: No

Reviewer #2: No

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Patient perspectives of the Self-management and Educational Technology tool for Atrial Fibrillation (SETAF): a mixed-methods study in Singapore

PONE-D-21-19770R1

Dear Dr. %Brigitte Fong Yeong Woo%,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Kind regards,

Muhammad Junaid Farrukh

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

dear author, thank you for addressing all the comments by the reviewers. i am happy to say that your manuscript is now suitable for publication.

Reviewers' comments: