PONE-D-21-22519Health and economic burden of foodborne zoonotic diseases in Amhara region, EthiopiaPLOS ONE

Dear Dr. Mekonnen,

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Bijaya Kumar Padhi, PhD, MPH

Academic Editor

PLOS ONE

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Additional Editor Comments (if provided):

This manuscript investigates health and economic burden of foodborne zoonotic diseases in Amhara region, Ethiopia. I commend the authors for conceptualizing this study, as the findings certainly add value to the literature. I have following comments:

1) The title of the manuscript should be framed as per STROBE guideline.

2) Psychometrics of the survey instruments should be provided.

3) Sample size calculations including power analysis should be provided

4) Authors said they used multiple logistic regression model. However, there is a lack of clarity on what basis the model was built. Whether they used a-priori hypothesis or any stepwise input of parameters. This information should be provided in data analysis section.

5) Table#5: please correct title of the table as per the data.

Reviewers' comments:

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Comments to the Author

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The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: No

Reviewer #2: Yes

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5. Review Comments to the Author

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Reviewer #1: Comments on the article reviewed

Material and methods:

• What is meant by projected population?

• Sample size and sampling method not properly documented. How 435 households were selected from 3 towns and method of recruitment of the respondents in the study is not clear.

• The term “haphazardly recruited” is not statistically correct.

• Animal source food consumption habits should be documented in either introduction or results or discussion.

• Grammatical errors are there in the text. It should be written in past tense but at some places, it is written in present or future tense.

• In data management and data analysis, write down the methods/software used e.g. Excel, SPSS etc.

Results

• Did not discuss the socio-demographic profile of the respondents in the starting of the results.

• Have not mentioned the risk factors or food consumption habits here.

Discussion

• Comparison with similar earlier studies is not sufficient.

Overall remarks

• The study findings are good in terms of health and economic burden. But need to rectify the material and methods. Also there is need to pay focus on risk factors and food consumption habits. Also give recommendations based on the findings of the study.

Reviewer #2: line 31- delet is and include 'may be'

line - 97- insert 'literature' after the word no

I had made corrections in the sticky notes and uploaded the pdf paper

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Reviewer #1: No

Reviewer #2: Yes: AMARENDRA MAHAPATRA

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Attachments

Attachment

Submitted filename: PONE-D-21-22519_reviewer.pdf

Health and economic burden of foodborne zoonotic diseases in Amhara region, Ethiopia

PONE-D-21-22519R1

Dear Dr. Mekonnen,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Kind regards,

Bijaya Kumar Padhi, PhD, MPH

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments: