PONE-D-21-03070

The Magnitude of Neonatal Near Miss and Associated Factors among Live Births in Public Hospitals of Jimma Zone, Southwest Ethiopia, 2020: A Facility-based cross-sectional study

PLOS ONE

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PLOS ONE

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Partly

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: I Don't Know

Reviewer #3: No

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3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: No

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4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Good start for unsual topic , I would suggest to have a wider study covering bigger population with defferent ethnic groups and socieconomic status , Ante natal care and follow up is crucial in such studay and has to be focused on

Reviewer #2: this article is very valuable because Neonatal Near Miss( NNM) data has not been collected in developing countries. Sample size is very large (260 cases) and very precisely analyzed. Even though NNM is due to only the maternal pregnancy conditions (social factors are very important) , the value of this study won't fade.

Reviewer #3: This manuscript reports the percentage of neonatal near miss and investigates the associated risk factors in public hospitals of Jimma Zone, Southwest Ethiopia with a facility-based cross-sectional study in 2020. I have below comments.

For the sample size, with the given assumptions (the prevalence of NNM of 50%, 5% margins of error), the sample size should have been 264 to guarantee the width of 95% confidence interval within +/-5% (corresponding to the planed 5% margins of error). With 10% non-response rate, the final sample size of 293 should have been planned. Please explain the discrepancy sample size calculation. N=255 to 260 would be good for a prevalence of NNM of ~20%. From the results on page 10, the NNM% in this study area was 26.7%. Is it a post-study calculation for the 5% margins of error?

From the results on page 10, the NNM% in the study area was 26.7% and (95%CI: 21.6%-32.5). Please add % after 32.5.

Are the selected four hospitals comparable on clinical function and the level of health care? Please provide the NNM% by hospital and compare other obstetric characteristics of respondents among hospitals. Are there any potential cluster effect by hospital? If yes, the cluster effect needs to be considered in the logistic regression.

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Reviewer #1: Yes: Sameh Abozaid

Reviewer #2: No

Reviewer #3: No

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The Magnitude of Neonatal Near Miss and Associated Factors among Live Births in Public Hospitals of Jimma Zone, Southwest Ethiopia, 2020: A Facility-based cross-sectional study

PONE-D-21-03070R1

Dear Dr. Hailegebireal,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Kazumichi Fujioka

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #3: All comments have been addressed

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2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #3: (No Response)

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3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #3: (No Response)

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4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #3: (No Response)

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5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #3: (No Response)

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6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #3: (No Response)

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7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #3: No