PONE-D-20-33796

Cumulative incidence of midline incisional hernia and its surgical treatment after radical cystectomy and urinary diversion for bladder cancer: A nation-wide population-based study

PLOS ONE

Dear Dr.Liedberg,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Comments and questions;

1- Please comment and add information about postoperative ‘’ileus’’ incidence and correlation with MIH.

2-  There is some punctuation and printing mistakes in the text as in page 3 line  99 ‘’preforming’’!.  Please check and consider for editing and proofreading.

3- Please add comment about follow-up time that is 2.3 years. Is it sufficient or not? 

4- I would like to know that did ERAS protocol use in study group If yes, what was ERAS protocol a relation with MIH?

5- In discussion section, ‘’limitation’’ part must be in last paragraph of this section.

6-In discussion section, you have to discuss your results with literature; for example in seconda paragraph; there is no reference!

7- In this study authors reported that robotic surgery increased risk of MIH by two fold. Please ad a comment about intrabdominal pressure and its effects on radical cystectomy and also MIH.

8- In table 1a, please correct in order for ‘’Previous inguinal hernia repair; No , Yes ...results. 

9- The resolutions of Figure 1a and 1b are insufficient; I could not read the details of these figures.

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We look forward to receiving your revised manuscript.

Kind regards,

Emre Bozkurt

Academic Editor

PLOS ONE

Additional Editor Comments:

Dear author,

Thank you for your well-designed manuscript. It needs some corrections before acceptance for publishing.

1- Please comment and add information about postoperative ‘’ileus’’ incidence and correlation with MIH.

2- There is some punctuation and printing mistakes in the text as in page 3 line 99 ‘’preforming’’!. Please check and consider for editing and proofreading.

3- Please add comment about follow-up time that is 2.3 years. Is it sufficient or not?

4- I would like to know that did ERAS protocol use in study group If yes, what was ERAS protocol a relation with MIH?

5- In discussion section, ‘’limitation’’ part must be in last paragraph of this section.

6-In discussion section, you have to discuss your results with literature; for example in seconda paragraph; there is no reference!

7- In this study authors reported that robotic surgery increased risk of MIH by two fold. Please ad a comment about intrabdominal pressure and its effects on radical cystectomy and also MIH.

8- In table 1a, please correct in order for ‘’Previous inguinal hernia repair; No , Yes ...results.

9- The resolutions of Figure 1a and 1b are insufficient; I could not read the details of these figures.

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Have the authors made all data underlying the findings in their manuscript fully available?

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Reviewer #1: Yes

Reviewer #2: Yes

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English?

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Reviewer #1: Yes

Reviewer #2: Yes

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Line 139: "-" sign is missing in the URL, please correct the URL as https://www.R-project.org/

Line 227-247: Please move the paragraph about limitations of the letter to the final part of discussion section

Reviewer #2: Dear authors,

This is a valuable orginal article about incidence of midline incisional hernia in surgery after radical cystectomy and urinary diversion for bladder cancer from Sweden. Thank you for your great effort but there are some concerns about the study.

Comments to authors;

1- Please comment and add information about postoperative ‘’ileus’’ incidence and correlation with MIH.

2- There is some punctuation and printing mistakes in the text as in page 3 line 99 ‘’preforming’’!. Please check and consider for editing and proofreading.

3- Please add comment about follow-up time that is 2.3 years. Is it sufficient or not?

4- I would like to know that did ERAS protocol use in study group If yes, what was ERAS protocol a relation with MIH?

5- In discussion section, ‘’limitation’’ part must be in last paragraph of this section.

6-In discussion section, you have to discuss your results with literature; for example in seconda paragraph; there is no reference!

7- In this study authors reported that robotic surgery increased risk of MIH by two fold. Please ad a comment about intrabdominal pressure and its effects on radical cystectomy and also MIH.

8- In table 1a, please correct in order for ‘’Previous inguinal hernia repair; No , Yes ...results.

9- The resolutions of Figure 1a and 1b are insufficient; I could not read the details of these figures.

Sincerely yours

**********

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Reviewer #1: No

Reviewer #2: No

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Cumulative incidence of midline incisional hernia and its surgical treatment after radical cystectomy and urinary diversion for bladder cancer: A nation-wide population-based study

PONE-D-20-33796R1

Dear Dr. Liedberg,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Emre Bozkurt

Academic Editor

PLOS ONE