Peer Review History
Original SubmissionJune 28, 2020 |
---|
PONE-D-20-19927 Patterns and determinants of modern contraceptive discontinuation among women of reproductive age: Analysis of Kenya Demographic Health Surveys, 2003–2014 PLOS ONE Dear Dr. Ontiri, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Sep 28 2020 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file. Please include the following items when submitting your revised manuscript:
If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter. If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols We look forward to receiving your revised manuscript. Kind regards, Catherine S. Todd Academic Editor PLOS ONE Journal Requirements: When submitting your revision, we need you to address these additional requirements. 1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and Additional Editor Comments (if provided): In addition to the points raised by the reviewers, I recommend making both the Introduction and Discussion more concise and reading through to edit areas with awkward phrasing (such as over-use of the word "majority" in the first part of the Results or using colloquial expressions like "backed-up"). Please clarify how "in need" was defined for the purposes of this analysis when determining which women were retained. While the focus of the paper is to report discontinuation, it is difficult to put these rates into perspective without also having data for method prevalence/use so please add this to the Results. Last, I would like to see greater nuance in contextualizing discontinuation rates. Were women who used the IUCD older overall and thus using the IUCD to limit rather than space? These women may have different thresholds or reasons for discontinuation as compared to women who are using COCs provided at the community level. For the expanded community-level provision of some short-acting methods, how likely is supply chain to factor into continuation vs. actual rejection of the method? Overall, this is a well-written manuscript and if the issues raised here and with the reviewers are addressed, should soon be acceptable for publication. [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. Reviewer #1: No Reviewer #2: Yes ********** 2. Has the statistical analysis been performed appropriately and rigorously? Reviewer #1: I Don't Know Reviewer #2: Yes ********** 3. Have the authors made all data underlying the findings in their manuscript fully available? The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified. Reviewer #1: Yes Reviewer #2: Yes ********** 4. Is the manuscript presented in an intelligible fashion and written in standard English? PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here. Reviewer #1: Yes Reviewer #2: Yes ********** 5. Review Comments to the Author Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters) Reviewer #1: This is a nice paper that utilized the complex DHS contraceptive calendar data to look at trends in contraceptive discontinuation rates in Kenya over three surveys. While I think the overall analysis and interpretation are sound, there are several key areas for the authors to improve, outlined below. The main issues are 1) the DHS dataset is complex, while also having potential concerns about validity given the reliance on 5 year recall, month-by-month for women. The authors need to explain this in a little more detail to both help the reader understand the complexity and to address head-on concerns about the validity of the interpretation. 2) the authors need to describe the statistical test and results they did to compare the trend of contraceptive discontinuation rates across the surveys. Line 95: Change the sentence “Kenya’s 2003 DHS of 2003” to not repeat the year. Overall, I think the introduction did a good job of providing important context to this study, however it becomes repetitive in the third paragraph (lines 65-72 state the same concept—contraceptive discontinuation while not wanting pregnancy—in multiple ways), and does not describe the strengths and weaknesses of the contraceptive calendar to allay readers’ potential concerns about the strength of the data. Materials and Methods: Please add a sentence about how contraceptive calendar data is collected/organized (recall of family planning need and contraceptive use for each month for the previous 5 years). Line 145/6: The sentence. “the datasets for 2003 and 2014 were first converted into an event file because the data was calendar data” is not clear. Results: Line 176-177: Could the authors calculate the statistical significance of the decrease in contraceptive discontinuation across the three time periods? This is also stated as the third sentence in the discussion (“no significant change”, but no discussion of whether a statistical test was used). Table 2 would be improved with actual numbers, so we can see what proportion of the population was using each method. Table 3: The ** and *** are not defined on the table. Table 4: The authors need to describe the decision to classify “it’s up to god, or fatalism” as an effect modifier and the rationale for excluding it from the analysis. Table 5 would be more accurately titled something like “Difference in method method continuation rates by reason, among women in need of contraception in Kenya between 2003 and 2014.” Discussion: Line 240: “A declined in contraceptive discontinuation between 2008 and 2014 was observed” seems to belie the preceding statement, lines 237-238, stating that no significant change was observed between 2003 and 2014—there are no statistical tests shown that support those statements. Reviewer #2: Comments on PONE-D-20-19927 This paper addresses an important topic. It is well-written, nicely framed, and uses appropriate analytical methods. It was a pleasure to read. I have two primary comments that I raise for the authors’ consideration in their treatment of the discussion/conclusion and abstract, followed by several very minor comments. Recommendations to prioritize short-term method users and young women seem to come from the finding that these users discontinue at higher rates than users of other methods/older women. However, discontinuation is not necessarily bad or a signal that something in wrong. Just discontinue while still in need (as the authors themselves point out in the introduction). There may be a selection effect: young women choosing condoms because it is easy to discontinue these methods when needs change. Focusing on these women/long-term methods writ large could actually risk ignoring their needs and impairing informed choice. This is more nuanced than is expressed in the abstract (the discussion does a slightly better job of this). I like the focus on resupply of short-term methods. Similarly, the recommendation to focus on counseling because of the increasing share of reasons for discontinuation being side effects. 1. Did the authors analyze whether the relative increase in side effects as a reason is accompanied or not by an absolute increase in this reason? I.e. are more women discontinuing due to side effects? (Same Q for wanting a more effective method). I’m wary of responding to concerns of side effects with better counseling about side effects. There is a large literature (more developed in high-income countries, but existing globally) about the medical establishment discounting women’s reports of pain and other symptoms. There is also a literature about women’s experiences with side effects. The DHS measure “side effects/health concerns” cannot distinguish whether it is women’s experiences or fears of side effects. We should be careful not to assume that it’s all fears in women’s heads. How do the recommendations to enhance counseling, particularly on side effects, respond to women’s needs if it is women’s experiences of side effects prompting discontinuation? What other recommendations might we consider to ensure that women who experience side effects with their selected method nonetheless have their contraceptive needs met? The issues of counselling and side effects should be a little more developed in the discussion and conclusions section. Minor comments: Data are available through The DHS Program website. MEASURE DHS was an old contract and references to that name should be updated. Likewise, ICF International is now ICF. Proofread: In at least one instance, the 2008-09 Kenya DHS appears as “2008/8” (p2, line 27). Do you want more consistency between the terms “family planning” and “contraception” (or modern contraception) or is this distinction intentional? Is uptake distinguishable from use? I believe, when discussing prevalence, use may be the more accurate term (p5, line 89). P6, line 122: Do you mean “adoption” instead of “application”? P7, line 126: It would more consistent to use “episodes” in lieu of “incidents”. Can Table 1 be formatted to have some separation between or better alignment between the N and (%)? It is a little difficult to read as is. When discussing changes in 12-month discontinuation rates across surveys (p10), it may be worth noting any substantial shifts in the method mix over that time period. Please use aHR consistently. On p11, lines 199-200 refer to the aHR, but have it labeled HR, making it unclear whether it is the crude or adjusted hazard rate, without referring to the table. (Alternately, the crude HRs could be removed from Table 3.) In Table 4 (p13), the na* on the row for “up to God/fatalistic” is in bold instead of plain text. Presentation of data on reasons for discontinuation (p13) exclude all fertility/need-based reasons. I assume that these reasons make up the difference between the sum of the reasons presented in Table 4 and 100%, i.e. that the authors are presenting the relative share of each reason to all reasons for discontinuation. This should be clarified, particularly if I am wrong in this assumption. In the discussion (p16), the authors summarize their results in terms of likelihoods. While there is a correspondence between likelihoods and hazards or hazard ratios, technically, the authors calculated the latter, not the former. I’m not sure this is a point worth getting worked up about, though. ********** 6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy. Reviewer #1: No Reviewer #2: Yes: Dr. Kerry L.D. MacQuarrie [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.] While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.
|
Revision 1 |
PONE-D-20-19927R1 Patterns and determinants of modern contraceptive discontinuation among women of reproductive age: Analysis of Kenya Demographic Health Surveys, 2003–2014 PLOS ONE Dear Dr. Ontiri, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Nov 26 2020 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file. Please include the following items when submitting your revised manuscript:
If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter. If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols We look forward to receiving your revised manuscript. Kind regards, Catherine S. Todd Academic Editor PLOS ONE Additional Editor Comments (if provided): My thanks to the authors for responding to most of the reveiwers' comments. Please kindly address the minor edits requested by Reviewer 1 and this manuscript will then be acceptable for publication. [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation. Reviewer #1: All comments have been addressed Reviewer #2: (No Response) ********** 2. Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. Reviewer #1: (No Response) Reviewer #2: Yes ********** 3. Has the statistical analysis been performed appropriately and rigorously? Reviewer #1: Yes Reviewer #2: Yes ********** 4. Have the authors made all data underlying the findings in their manuscript fully available? The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified. Reviewer #1: Yes Reviewer #2: Yes ********** 5. Is the manuscript presented in an intelligible fashion and written in standard English? PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here. Reviewer #1: Yes Reviewer #2: Yes ********** 6. Review Comments to the Author Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters) Reviewer #1: The authors have adequately addressed all of both Revieweers' concerns in the text and additions to the tables. Reviewer #2: I am largely satisfied with the authors’ changes and appreciate their efforts to respond to the reviewers’ comments so conscientiously. I note a few suggested clarifications for the authors. On page 5, line 105, the authors refer to the method mix, but it appears that everything in lines 101-108 is prevalence of each method (the percentage of women using each method) rather than method mix (the percentage of use contributed by a particular method). Optional: Also in this section, the authors not trends that are both substantial and likely statistically significant (e.g. increase of injectable use from 14.3% to 21.6% in 2003-2008/9) and those that are not (e.g. decrease of pill use from 7.5% to 7.2%). If the authors would like to streamline the paper, this is one paragraph where some modest edits could help achieve that. On page 7, lines 149-150, the authors are technically correct that discontinuation while in need comprises women who discontinue while still at risk of becoming pregnant, do not want to become pregnant… However, isn’t this definition operationalized from the reasons for discontinuation (given in the second column of the calendar)? It would be helpful to clarify this and list which reasons comprise discontinuation while in need (e.g. husband disapproval, side effects, access, cost, wanted more effective method…) and those that do not comprise while in need (wanted to become pregnant, husband away/infrequent sex,…). Thank you for clarifying that percentages in Table 4 do not sum to 100% because the table excludes discontinuation due to no further need. Could the table titled be revised to read, “Reasons for discontinuation while still in need” rather than “…among women in need,” as this change would be more accurate? And could the authors add a footnote to the tables similar to their response to the reviewer, e.g. “Percentages do not sum to 100% since women who discontinued while not in need of contraceptives, including those who reported they wanted to become pregnant/experienced menopause (2003, 42.1% and in 2014, 46.5%) were excluded from the analysis.” ********** 7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy. Reviewer #1: No Reviewer #2: Yes: Kerry MacQuarrie [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.] While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step. |
Revision 2 |
Patterns and determinants of modern contraceptive discontinuation among women of reproductive age: Analysis of Kenya Demographic Health Surveys, 2003–2014 PONE-D-20-19927R2 Dear Ms. Ontiri, We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements. Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication. An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org. If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org. Kind regards, Catherine S. Todd Academic Editor PLOS ONE Additional Editor Comments (optional): I thank the authors for their attentive revisions and am pleased to accept this manuscript for publication. Reviewers' comments: |
Formally Accepted |
PONE-D-20-19927R2 Patterns and determinants of modern contraceptive discontinuation among women of reproductive age: Analysis of Kenya Demographic Health Surveys, 2003–2014 Dear Dr. Ontiri: I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department. If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org. If we can help with anything else, please email us at plosone@plos.org. Thank you for submitting your work to PLOS ONE and supporting open access. Kind regards, PLOS ONE Editorial Office Staff on behalf of Dr. Catherine S. Todd Academic Editor PLOS ONE |
Open letter on the publication of peer review reports
PLOS recognizes the benefits of transparency in the peer review process. Therefore, we enable the publication of all of the content of peer review and author responses alongside final, published articles. Reviewers remain anonymous, unless they choose to reveal their names.
We encourage other journals to join us in this initiative. We hope that our action inspires the community, including researchers, research funders, and research institutions, to recognize the benefits of published peer review reports for all parts of the research system.
Learn more at ASAPbio .