Peer Review History
Original SubmissionSeptember 4, 2019 |
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Performance of cardiopulmonary exercise testing for the prediction of post-operative complications in non cardiopulmonary surgery: a systematic review PONE-D-19-24934 Dear Dr. Ercole, We are pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it complies with all outstanding technical requirements. Within one week, you will receive an e-mail containing information on the amendments required prior to publication. When all required modifications have been addressed, you will receive a formal acceptance letter and your manuscript will proceed to our production department and be scheduled for publication. Shortly after the formal acceptance letter is sent, an invoice for payment will follow. 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During our internal evauation, the in-house editorial staff noticed that the date of the last electronic search was conducted on July 24th 2018. In order to ensure systematic reviews are comprehensive, unbiased and timely, the electronic database search should be conducted within the last 12 months of submission. At this time, we request that you please provide an updated search and include any new studies in your meta-analysis. Additionally, please provide a description of any assessment of research/methodological quality of the studies included in your meta-analysis, such as the use of the Newcastle-Ottawa scale for non-randomised studies. Additional Editor Comments (optional): The editor and all reviewers appreciated the clinical importance of your manuscript. The incorporation of patients with a broad spectrum of surgical interventions belonged to one of the major strengths of the paper. The editor and the reviewers believe that the manuscript will be useful in recognizing patients not at increased peri-operative risk and will facilitate the process of shared decision making and the allocation of resources. Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: Yes ********** 2. Has the statistical analysis been performed appropriately and rigorously? Reviewer #1: Yes Reviewer #2: Yes ********** 3. Have the authors made all data underlying the findings in their manuscript fully available? The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified. Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: Yes ********** 4. Is the manuscript presented in an intelligible fashion and written in standard English? PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here. Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: Yes ********** 5. Review Comments to the Author Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters) Reviewer #1: Stubbs and colleagues performed a critical review about the clinical impact of cardiopulmonary exercise testing for the prediction of post-operative complications in non cardiopulmonary surgery. In my opinion this systematic review is well structured and stresses the various advantages and drawbacks concerning preoperative functional risk evaluation. Reviewer #2: The authors made a huge effort to review the literature on the use of cpet for the prediction of post-operative complications for cardiorespiratory complications, 30 day or in-hospital death, and unplanned intensive care unit admission for non-cardiopulmonary surgery from 1993 until now. The review process including search strategy, inclusion and exclusion criteria, data extraction and prediction performance metrics is documented in detail, statistical analysis are robust. The high negative predictive values (96-100%) and poor positive predictive value (2.9-42.1%) and differences as a predictor of mortality between anaerobic threshold, VE/VCO2 and peak VO2 might have implications on perioperative assessment startegies in real life and may be of interest in the integrative multidisciplinary approach of preoperative patients. Therefore i would recommend to accept this paper. ********** 6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy. Reviewer #1: No Reviewer #2: No Reviewer #3: No |
Formally Accepted |
PONE-D-19-24934 Performance of cardiopulmonary exercise testing for the prediction of post-operative complications in non cardiopulmonary surgery: a systematic review Dear Dr. Ercole: I am pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department. If your institution or institutions have a press office, please notify them about your upcoming paper at this point, to enable them to help maximize its impact. If they will be preparing press materials for this manuscript, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org. For any other questions or concerns, please email plosone@plos.org. Thank you for submitting your work to PLOS ONE. With kind regards, PLOS ONE Editorial Office Staff on behalf of Dr. Gabor Kovacs Academic Editor PLOS ONE |
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