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Fig 1.

SEM image of (a) ZnO nanoparticles (b) ointment base (c) ointment (base:active 9:1, Carica papaya latex:Aloe 1:4) (d) ointment (base:active 7:3, Carica papaya latex:Aloe 1:2) (e) ointment (base:active 7:3, Carica papaya latex:Aloe 1:1) (f) ointment (base:active 7:3, Carica papaya latex:Aloe 4:1).

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Fig 1 Expand

Fig 2.

XRD patterns of the (a) individual components (b) and (c) ointment formulations.

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Fig 2 Expand

Fig 3.

FT-IR spectra of the materials.

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Fig 3 Expand

Fig 4.

Antioxidant activity (DPPH assay) of (a) Aloe barbadensis Miller gel, (b) Carica papaya latex powder, (c) ZnO nanoparticles.

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Fig 4 Expand

Table 1.

Blood assay results summary.

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Table 1 Expand

Table 2.

Absorbance values of Carica papaya latex powder in the protease assay.

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Table 2 Expand

Fig 5.

Zones of Inhibition against (A) Staphylococcus aureus (B) Escherichia coli (C)Variation of the zones of inhibition (in mm) against the test organisms by the tested samples at (a) 10 mg/mL, (b) 20 mg/mL, (c) 40 mg/mL (d) varied cream base ratios at 20 mg/mL.

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Fig 5 Expand

Table 3.

MIC, MBC, and MBC/MIC ratios for the test formulation against Escherichia coli and Staphylococcus aureus.

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Table 3 Expand

Fig 6.

Time-kill curves of Staphylococcus aureus (a-c) and Escherichia coli (d-f) against the tested samples.

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Fig 6 Expand