Fig 1.
Flowchart of inclusion and exclusion for osteoporotic fracture patients.
Table 1.
Baseline demographic and clinical features of 2,190 individuals with osteoporotic fractures stratified by ln-transformed homocysteine levels.
Table 2.
Univariate analyses of factors associated with serum parathyroid hormone (PTH).
Table 3.
Multivariable linear regression analyses of ln-transformed homocysteine (lnHcy) and serum parathyroid hormone (PTH) levels.
Table 4.
Threshold-effect analysis of the association between ln-transformed homocysteine (lnHcy) and serum parathyroid hormone (PTH) levels based on the two-piecewise linear regression model.
Fig 2.
Smoothed curve of the association between lnHcy and serum PTH.
Each short black tick on the x-axis represents one participant. The solid red line represents the fitted curve derived from a generalized additive model (GAM), and the blue shaded area indicates the 95% confidence interval. The model was adjusted for age, sex, BMI, hypertension, diabetes, albumin, creatinine, magnesium, smoking status, alcohol consumption, ASA classification, and admission season. Abbreviations: BMI, body mass index; ASA, American Society of Anesthesiologists.
Table 5.
Subgroup analyses of the association between ln-transformed homocysteine (lnHcy) and serum parathyroid hormone (PTH) levels according to clinical characteristics.