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Fig 1.

Partition survival model.

PartSA, partitioned survival approach.

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Table 1.

AIC and BIC of survival curve in two groups.

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Table 2.

Parameter distribution of survival curve in two groups.

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Fig 2.

Optimal curve fitting extrapolation of two treatment schemes.

A. Simulated PFS curve; B. Simulated OS curve.

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Table 3.

Model Parameters.

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Table 4.

Baseline results.

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Table 5.

Results of scenario analyses under different simulation time horizons.

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Table 6.

Effects of different simulation distribution approaches on the ICER.

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Table 7.

ICER values at different discount rates for drug prices.

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Fig 3.

Tornado diagram for one-way sensitivity analysis.

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Fig 3 Expand

Fig 4.

Acceptability curves.

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Fig 5.

Cost-effective scatter plot.

Results of Monte Carlo probabilistic sensitivity analysis showing incremental cost-effective of finotonlimab plus bevacizumab biosimilar versus sorafenib.

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