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Table 1.

Global Incidence and DALYs of ILD&PS and their AAPCs globally by gender, specific age group, SDI, and region from 1990 to 2021.

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Fig 1.

Joinpoint Regression analysis for global incidence of ILD&PS (A), prevalence (B), deaths (C) and DALYs (D) in adults aged 55 + years from 1990 to 2021.

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Fig 2.

The trends in incidence cases of ILD&PS in specific age group ranging from 55 years to 95 + years over 1990-2021.

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Fig 3.

Trends in the incidence of ILD&PS by sex and across age groups (55–95 + years) in 1990 and 2021.

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Fig 4.

Changes in total rates in incidence, prevalence, death, and DALYs for ILD&PS in both sexes combined, females and males individually, and in global and 5 SDI quintiles regions (1990–2021).

All countries and territories were categorized into five groups based on sociodemographic index quintiles: Low SDI, Low-middle SDI, middle SDI, High-middle SDI, and High SDI.

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Fig 5.

The DALYs rates stratified by SDI for ILD&PS globally and for 21 disease burden regions from 1990 to 2021.

The DALYs rates (based solely on SDI) are represented by the black line. For each region, the dots from left to right indicate annual estimates.

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Fig 6.

SDI correlation analysis of DALYs rates for 204 countries in 2021.

DALY rates for 2021 (based on SDI only) are indicated by the black line.

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Fig 7.

Global map of incidence (A), prevalence (B), deaths (C) and Prevalence DALYs (D) rates (per 100,000 population) in 2021 in 204 countries and territories.

Note: Base map from Natural Earth (public domain). Map created by the authors in R.

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Fig 8.

Trends in rates from 2019 to 2035, predicted using BAPC prediction models.

The rows, from top to bottom, show incidence, prevalence, and mortality rates, and the three columns correspond to males and females. Solid points represent observed data, while shaded bands illustrate the predicted distribution between the 2.5% and 97.5% quantiles. The projected mean is shown as a solid line, and the vertical dashed line indicates the start of the prediction period.

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