Table 1.
SOFA Score [22]. MAP: Mean arterial pressure, CNS: Central nervous system, GCS: Glasgow coma score. *Catecholamine doses = µg/Kg/min for, at least, 1 hour.
Fig 1.
Diagram of protein selection.
Table 2.
Characteristics of the study population. CRP: C-reactive protein.
Table 3.
Differentiated proteins analyzed between sepsis and NISIRS.
Fig 2.
Strings network of physiological interactions between the different proteins analyzed (https://string-db.org/).
Proteolysis (red), Innate immune response (green), Complement activation (blue), Response to lipopolysaccharides (pink), Blood coagulation (purple), Lipid metabolism (yellow), Other functions (grey).
Fig 3.
Mean absolute SHAP values of the logistic regression model.
Mean absolute SHAP values indicate the relative contribution (association strength) of each protein to the model output when discriminating between sepsis and NISIRS. Higher values denote stronger influence on the classification.
Fig 4.
Logistic regression coefficients (β, log-odds scale) for the discrimination between sepsis and NISIRS.
Positive coefficients indicate association with sepsis, while negative coefficients indicate association with NISIRS. Coefficients are reported on the log-odds scale.