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Table 1.

Criteria for inclusion of studies based on the Population, Exposure, Comparator, Outcome, Time (PECOT) framework.

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Fig 1.

PRISMA flow diagram of article selection for systematic review and meta-analysis of folate deficiency among adolescent girls 2025.

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Table 2.

Characteristics of the included studies and their proportion of folate defiecency among adolescent girls, 2025.

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Fig 2.

Forset plot for the proportion of folate defiecency among adolecent girls.

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Fig 3.

Forest plot result of subgroup analysis by WHO region for the proportion of folate defiecency among adolecent girls, 2025.

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Fig 4.

Forest plot result of subgroup analysis by publication year for the proportion of folate defiecency among adolecent girls, 2025.

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Fig 5.

Forest plot result of subgroup analysis by sample size for the proportion of folate defiecency among adolecent girls, 2025.

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Fig 6.

Forest plot result of subgroup analysis by type of biological sample for the proportion of folate defiecency among adolecent girls, 2025.

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Table 3.

Study-specific cut-off values for red blood cell and serum folate concentrations for the study the proportion of folate defiecency among adolecent girls, 2025.

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Fig 7.

Funnel plot for the study the proportion of folate defiecency among adolecent girls, 2025.

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Table 4.

Egger’s of Publication Bias of Included Studies in the Systematic Review and Meta-Analysis the Proportion of Folate Defiecency Among Adolecent Girls, 2025.

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Fig 8.

Trim and fill analysis result of the study the proportion for folate defiecency among adolecent girls, 2025.

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Fig 9.

Leave-one-out sensitivity analysis of pooled prevalence of folate deficiency among adolescent girls.

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Table 5.

Meta-regression analysis of study-level factors associated with heterogeneity in folate deficiency among adolescent girls.

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Table 6.

Certainty assessment for included outcomes for the folate defiecency among adolescent girls, 2025.

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