Fig 1.
Flowchart of patient selection for the study.
DM, diabetes mellitus; CLD, chronic liver disease.
Table 1.
Characteristics of the patients included in this study (N = 152).
Table 2.
Comparison of background characteristics between patients with and without DM among those with CLD (N = 152).
Table 3.
Comparison of body composition and physical function between patients with and without DM in CLD (N = 152).
Table 4.
Logistic regression analysis for impaired SLST (< 5 s) among patients with CLD and DM (n = 118).
Fig 2.
ROC curves for predicting SLST duration < 5 s in patients with CLD and DM (n = 118), using age, BMI, ECW/TBW, and KEF/weight as predictors. ROC curves for (a) age, (b) BMI, (c) ECW/TBW, (d) KEF/weight, and the combination of age, BMI, ECW/TBW, and KEF/weight using SLST < 5 s as the dependent variable. The results showed the following: age: AUC = 0.658, p = 0.014, cutoff = 74 years, sensitivity = 47.8%, specificity = 82.8%, PPV = 40.7%, NPV = 86.5%; BMI: AUC = 0.626, p = 0.035, cutoff = 27.9 kg/m², sensitivity = 60.9%, specificity = 76.3%, PPV = 38.9%, NPV = 88.8%; ECW/TBW: AUC = 0.733, p = 0.001, cutoff = 0.393, sensitivity = 73.9%, specificity = 68.8%, PPV = 37.0%, NPV = 91.4%; KEF/weight: AUC = 0.673, p = 0.003, cutoff = 0.54 kgf/kg, sensitivity = 82.6%, specificity = 47.3%, PPV = 27.9%, NPV = 91.7%; and, the combination of age, BMI, ECW/TBW, and KEF/weight: AUC = 0.795, p < 0.001, sensitivity = 60.9%, specificity = 87.1%, PPV = 53.8%, NPV = 90.0%. ROC, receiver operating characteristic; SLST, single-leg stance test; CLD, chronic liver disease; DM, diabetes mellitus; BMI, body mass index; ECW/TBW, extracellular water-to-total body water ratio; KEF, knee extension force; AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value.