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Fig 1.

Study cohort flowchart.

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Table 1.

Patient demographics.

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Fig 2.

Model-based cumulative incidence (Fine–Gray): escalation to ≥50 MME/day by eGFR category (death as competing event).

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Fig 2 Expand

Fig 3.

Model-based cumulative incidence (Fine–Gray): escalation to ≥90 MME/day by eGFR category (death as competing event).

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Fig 3 Expand