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Table 1.

Baseline characteristics of the selected cohort.

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Fig 1.

Prescription-Level Distribution of Drug–Drug Interaction Categories.

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Table 2.

Top Drug-Drug Interactions by Severity and Frequency.

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Fig 2.

Network of High-Frequency Drug–Drug Interactions with Severity Coding.

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Table 3.

Distribution and Severity of Drug–Drug Interactions Stratified by Sex and Age Group.

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Table 3 Expand

Table 4.

Prescription Volume, Polypharmacy, and Severity-Profiled Drug–Drug Interactions Across the Ten Highest-Volume Physician Specialties.

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Fig 3.

Multivariable linear regression for predictors of the number of DDIs in prescriptions.

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Fig 4.

Interaction-Adjusted Effects of Predictors on Drug–Drug Interaction Counts.

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Fig 5.

Estimated Effects of Predictors on the Likelihood of Contraindicated Drug–Drug Interactions.

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