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Fig 1.

Geographical variations in the IHD burden attributable to high BMI among young adults and adolescents worldwide. Republished from the Resource and Environment Science and Data Center (https://www.resdc.cn/) under a CC BY license, with permission from the Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, original copyright [2025]

(A) Global distribution of DALYs due to IHD per 100,000 population among individuals aged 20-49 years. (B) Global distribution of mortality rates due to IHD per 100,000 population among individuals aged 20-49 years.

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Fig 2.

Diverging epidemiological trends in high BMI-Attributable IHD burden across sociodemographic contexts.

(A) Global trends in DALYs attributable to high BMI from 1990 to 2021. (B-F) DALY trends across different SDI levels from 1990 to 2021, including low SDI, low-middle SDI, middle SDI, high-middle SDI, and high SDI countries.

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Fig 3.

Age-period-cohort trends.

Heterogeneous age-period-cohort trends in high BMI-Attributable IHD burden across sociodemographic contexts.

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Fig 4.

Age effects on the epidemiological transition of high BMI-Attributable IHD burden across sociodemographic contexts.

(A) Age-specific rates (per 100,000 population) of ischemic heart disease attributable to high body mass index. (B) Relative risk ratios across age groups, providing insights into age, period, and cohort effects.

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Fig 5.

Divergent period and cohort effects on the epidemiological transition of high BMI-Attributable IHD burden across sociodemographic contexts.

(A) Period effects, representing the influence of time-varying factors on the ischemic heart disease burden. (B) Cohort effects, capturing the differences in disease burden across birth cohorts.

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Fig 6.

Decomposition analysis.

Heterogeneous drivers of health burden transitions across sociodemographic contexts.

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Fig 7.

Projected GBD to 2044.

Widening gender disparities in total cases and age-standardized rates.

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