Fig 1.
Evaluation of plasma concentrations of urea (A) and HCit (B) in WT (grey bars) and MPO-/- (open bars) mice.
Values were expressed as means ± standard deviations. Statistical significance was determined by Two-way ANOVA followed by Tukey’s multiple comparisons test. **: p < 0.01, ***: p < 0.0001, (ns) non-significant.
Fig 2.
HCit accumulation in skin (A) and aorta (B) of WT and MPO-/- mice.
Dark lines represent the evolution of average HCit values at each age while grey areas represent 95% confidence intervals of the values.
Table 1.
Evolution of aorta/skin HCit ratios during ageing in wild-type and MPO-/- mice.