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Table 1.

Overview of the burden of MND in China and worldwide.

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Table 1 Expand

Fig 1.

The APCs of the ASIR, ASPR, ASMR, and ASDR of MND in China from 1990 to 2021, with asterisks (*) indicating p values < 0.05, indicating statistically significant results.

(a) ASIR, (b) ASPR, (c) ASMR, (d) ASDR.

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Fig 1 Expand

Fig 2.

The APCs of the ASIR, ASPR, ASMR, and ASDR of MND worldwide from 1990 to 2021, with asterisks (*) indicating p values < 0.05, indicating statistically significant results.

(a) ASIR, (b) ASPR, (c) ASMR, (d) ASDR.

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Fig 2 Expand

Fig 3.

Comparison of the ASIR, ASPR, ASMR, and ASDR trends of MND in China and worldwide from 1990 to 2021.

(a) China, (b) Global.

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Fig 3 Expand

Fig 4.

Comparative analysis of age-stratified incidence rates, prevalence rates, mortality rates, and DALYs, including crude rate evaluations, in China during 1990 and 2021.

(A) Incidence, (B) prevalence, (C) mortality, (D) DALYs. The bar charts display counts, whereas the lines depict crude rates of sex-based disparities in the burden of MND among distinct age groups within China.

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Fig 4 Expand

Fig 5.

Comparative analysis of global age-stratified incidence rates, prevalence rates, mortality rates, and DALYs, including crude rate evaluations, for 1990 and 2021.

(A) Incidence, (B) prevalence, (C) mortality, (D) DALYs. The bar charts display counts, whereas the lines depict crude rates of sex-based disparities in the burden of MND among distinct age groups worldwide.

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Fig 5 Expand

Fig 6.

Comparison of the MND incidence, prevalence, mortality, and DALY rates of male and female individuals across various age ranges in China in 1990.

(a) Prevalence rate, (b) incidence rate, (c) mortality rate, (d) DALY rate.

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Fig 6 Expand

Fig 7.

Comparison of the MND incidence, prevalence, mortality, and DALY rates of males and females across various age ranges in China in 2021.

(a) Prevalence rate, (b) incidence rate, (c) mortality rate, (d) DALY rate.

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Fig 7 Expand

Fig 8.

Comparative analysis of annual case counts and age-standardized incidence rate, prevalence rate, mortality rate, and DALY rate between males and females in China from 1990 to 2021.

(A) Prevalence and ASPR, (B) incidence situations and ASIR, (C) mortality and ASMR, (D) DALYs and ASDR. Bar graphs display frequencies; curves denote age-standarized rates.

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Fig 8 Expand

Fig 9.

Comparative analysis of annual case counts and age-standardized incidence rate, prevalence rate, mortality rate, and DALY rate between males and females worldwide from 1990 to 2021.

(A) Prevalence and ASPR, (B) incidence situations and ASIR, (C) mortality and ASMR, (D) DALYs and ASDR. Bar graphs display frequencies; curves denote age-standardized rates.

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Fig 9 Expand