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Fig 1.

Flow diagram of study inclusion.

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Fig 2.

Distribution of randomized controlled trials across different CBDIs.

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Fig 3.

The risk of bias assessment.

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Fig 4.

Forest plot of the comparative effects of CBDIs on outcomes.

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Table 1.

Surface Under the Cumulative Ranking Curve (SUCRA) rank of the outcomes.

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Table 1 Expand

Fig 5.

Plots of the Surface Under the Cumulative Ranking Curve (SUCRA) for outcomes.

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Fig 5 Expand

Fig 6.

Funnel plot of each outcome indicator.

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Fig 6 Expand

Table 2.

GRADE summary of evidence.

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Table 2 Expand