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Table 1.

Data collected in the TBPed study.

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Fig 1.

Study procedures performed in the hospital-based study arm (panel A) and in the outpatient-based study arm (panel B).

MGIT = Mycobacteria Growth Indicator Tube.

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Fig 2.

The Brazilian Ministry of Health’s score system for predicting PTB in children. RMT = rapid molecular test; TB = tuberculosis; TST = tuberculin skin test, IGRA = Interferon-Gamma Release Assay, BMI = Body Mass Index. More than or equal 40 points (very likely diagnosis) = it is recommended to start TB treatment; 30–35 points (possible diagnosis) = indicative of TB; it is advised to initiate treatment, at medical discretion; Less than or equal 25 points (diagnosis is unlikely) = investigation of the child should be continued.

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Table 2.

Study aims, statistical analysis plan, missing data management, and outcomes.

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Table 2 Expand