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Fig 1.

Transcription patterns following decapeptide exposure. A) RNA patterns for top 22 species following 1 hr exposure to decapeptide (62 pmole) for enteroids. Duplicate lanes – control lanes on left, decapeptide lanes on right. (Similar profiles were seen up to 4 hrs post-exposure.) B) RNA patterns for top 22 species 1 hr post-exposure to decapeptide (62 pmole) for HEK293 cells. Two sets of data showing control on left, exposure on right for each set.

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Fig 1 Expand

Fig 2.

Heat map of transcription patterns using full-length SAA1 (4.3 mµmole) and HEK293 monolayers for up to 2 hrs.

Summary of triplicate studies. Columns correspond to 0, 30, 60, 120 minute time points. The left 4 columns are controls; the right 4 are from exposed cells. Transcript identities indicated on the right. See also Table 1 for details of prominent changes.

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Table 1.

Prominent Transcript Changes for HEK293 cells exposed to full-length human SAA.

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Table 1 Expand

Fig 3.

Comparison of N-terminal sequences for mSAA and SAA1.

The TFLK sequence (overlined) is not present in human SAA1. The only correspondences for this region are indicated by the dots.

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Fig 3 Expand