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Table 1.

Demographic, clinical, functional and outcomes distribution between the groups.

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Table 1 Expand

Table 2.

Distribution of MUC5B rs35705950 genotypes and association with idiopathic pulmonary fibrosis (IPF).

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Table 2 Expand

Fig 1.

Baseline pulmonary function (FVC) according to MUC5B rs35705950 genotype in patients with idiopathic pulmonary fibrosis (IPF).

Legend: Box-and-strip plots display forced vital capacity (FVC) in liters (A) and percent predicted (B) stratified by genotype (G/G, G/T, T/T). Central circles show marginal means from linear models adjusted for age, sex, and ethnicity, with covariates held at observed means/proportions; error bars indicate 95% CI. Pairwise comparisons were Tukey-adjusted. T-allele carriers exhibited lower FVC than G/G.

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Table 3.

Multivariable Cox proportional hazards for all-cause mortality in idiopathic pulmonary fibrosis (IPF).

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Table 3 Expand

Fig 2.

Kaplan-Meier survival by MUC5B rs35705950 genotype in idiopathic pulmonary fibrosis (IPF).

Legend: Step plots show survival from symptom onset stratified by genotype. Curves suggest lower survival among T-allele carriers, although differences were not significant (overall log-rank χ² = 1.07; p = 0.30). Time in years; Numbers at risk are provided in the Supplement.

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Fig 2 Expand