Fig 1.
Subgroup categorization based on total hand OA score, total lower extremity OA score and total multimorbidity score.
Multimorbidity score represents those with 2 or more self-reported diagnoses across 21 health conditions. Green (— —) indicates the subgroup has the health condition. Red (– – –) indicates the subgroup does not have the health condition. Subgroups range from healthiest (Subgroup A represents those without OA or multimorbidity) to the least healthy (Subgroup H represents those with lower extremity OA, hand OA and multimorbidity).
Table 1.
Mean and standard deviation (SD) of C-Reactive Protein (CRP) values for each subgroup (A to H) for females and males.
Fig 2.
Flowchart of participant inclusion and exclusion, based on availability of complete data.
Subgroup refers to self-report status (yes/no) for the presence of lower extremity osteoarthritis (OA), hand OA and multimorbidity. CRP, C-reactive protein; CES-D, Center for Epidemiological Studies Short Depression scale; DXA, Dual-Energy X-Ray Absorptiometry.
Fig 3.
Violin plot showing the distribution of CRP values (mg/L) (vertical axis), separated by sex (horizontal axis).
A total of 541 (4.0%) females and 386 (2.9%) males had levels greater than 10 mg/L, which in a clinical context, are indicative of clinically significant inflammation.
Table 2.
Regression models for females and males used to explain grip strength, mobility index, DXA whole body fat mass, DXA whole body fat percent, DXA whole body lean mass, DXA trunk fat percent, DXA appendicular fat mass index, DXA appendicular lean mass index.
Table 3.
Unstandardized and standardized β coefficients (95%CI) for log-CRP for model 2 (covariates† + log-CRP) for females and males.
Table 4.
Unstandardized and standardized β coefficients (95%CI) for log-CRP for model 3 (covariates† + log-CRP + log-CRP × subgroup) for females and males.
Table 5.
Unstandardized and standardized β coefficients (95%CI) for each covariate for females and males with DXA whole-body fat percent as the dependent variable.
Fig 4.
Plot comparing the standardized β coefficients (95%CI) of the associations between dependent variables reflecting body composition and physical function with the independent variable of log-CRP for model 2 (covariates + log-CRP) for females and males.