Fig 1.
Pulmonary transit time analysis.
Regions of interest (not shown) are manually traced in the right ventricle (RV) and the left ventricle (LV) to create the signal intensity (SI) vs. time curves. The pulmonary transit time (PTT) corresponds to the difference between the onsets, selected as the points where the signal surpasses 10% of the maximum values.
Table 1.
Baseline clinical, TTE, CMR, and RHC parameters.
Table 2.
Pulmonary circulation parameters correlations.
Fig 2.
Box-plot comparison of subgroups with different diastolic function.
Patients with diastolic dysfunction grade III (restrictive filling pattern, group 3) showed significantly longer PTT compared to subgroups without diastolic dysfunction (group 0) and with diastolic dysfunction grade II (impaired relaxation, group 2).
Fig 3.
Receiver operating characteristics for pulmonary transit time and pulmonary hypertension.
Receiver operating characteristics demonstrating the ability of pulmonary transit time (PTT) to determine pulmonary hypertension with a threshold of 8.62, sensitivity of 53.2%, specificity of 86.5%, and an area under the curve of 72.7%.
Fig 4.
Receiver operating characteristics for corrected pulmonary transit time and pulmonary hypertension.
Receiver operating characteristics demonstrating the ability of corrected pulmonary transit time (PTTc) to determine pulmonary hypertension with a threshold of 8.52, sensitivity of 70.2%, specificity of 81.1%, and an area under the curve of 75.3%.