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Fig 1.

Procedure real-time images.

US-guided cryoprobe (white arrow) centring within the FA (a) and subsequent ice ball (arrowhead) formation (b).

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Fig 1 Expand

Fig 2.

Patient’s flow (n number of fibroadenomas).

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Table 1.

Patient characteristics.

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Table 2.

Number of FAs per patient.

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Table 2 Expand

Fig 3.

Fibroadenoma (FA) localisation.

Distribution of the different FAs by side (outer/ inner) and quadrant location (a). Two examples (depicted on the same fig), one of a patient with 2 FAs in close proximity in the left breast (green circles marked 1 and 2) and one of a 48-year-old patient with 2 FAs, one in the left breast and one in the right breast (blue circles marked 1 and 2) (b).

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Table 3.

FA characteristics at baseline and procedure features.

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Table 3 Expand

Fig 4.

Median percent FA volume reduction.The median percentage volume reduction of FA at 6 ± 1.5 and 12 ± 1.5 months was calculated for all FAs that had data at either time point (see Methods for details).

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Table 4.

Characteristics of patients with a lesion(s) larger than 40 mm.

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Table 4 Expand

Fig 5.

Volume reduction for lesions larger than 40 mm.

The graph presents the percentage volume reduction over time following cryoablation of eight fibroadenomas (FAs) in seven patients. Each line represents an individual FA with available follow-up measurements. Volume reduction was calculated at each time point where post-procedural data were available (see Methods for more details).

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