Fig 1.
Antioxidant activity of different fractions of R. mucronate.
Percentage inhibition (scavenging) of DPPH was plotted against concentrations of samples. Data were recorded for three times (S1 Table) and presented as mean SEM. IC50 was determined by identifying the concentration at which 50% inhibition occurred.
Table 1.
Analgesic activity of HRM, DRM and ERM using acetic acid induced writhing model in mice.
Fig 2.
Antidiabetic effect of fractions HRM, DRM and ERM on streptozotocin induced diabetic mice.
Values were expressed in Mean ± SEM. 0.5% Methyl cellulose was received by the diabetic control group (Group I) and glibenclamide 5 mg/kg was received by reference group (Group II) and HRM, DRM and ERM were given to Group-III, Group-IV and Group-V respectively at the dose of 200 mg/kg. *p < 0.05 indicates significance compared with control group.
Table 2.
Antimicrobial activity of test samples of R. mucronata.
Fig 3.
Zone of inhibition of different fractions of R. mucronata.
Fig 4.
In -vitro cytotoxic activity of bleomycin, HRM, DRM and ERM in Hella cell line.
The line diagram shows the percentage cell death and the bar diagram represents the IC50 values of different extracts.
Table 3.
In-vivo cell growth inhibition of the extracts HRM, DRM and ERM against EAC cell.
Fig 5.
Structure of isolated compounds (1-3) from Rhizophora mucronate.
Compound 1: N-trans-para-caffeoyl-tyramine [30], compound 2: β-sitosterol [31] and compound 3: rutin [32]. The NMR Spectra of the compounds are available in the Supporting information.