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Fig 1.

Flow chart of the study population.

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Table 1.

Baseline characteristics of participants classified by the blood urea nitrogen to creatinine ratio.

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Table 2.

Cox regression models for the association between the BUCR and 28-day in-hospital mortality.

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Fig 2.

Cumulative incidence curves for 28-day in-hospital mortality by BUCR based on competing risk analysis.

BUCR: blood urea nitrogen-to-creatinineratio.

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Fig 3.

Restricted cubic spline models were used to analyze the relationship between BUCR and 28-day hospital mortality.

Adjusted age, gender, ethnicity, BMI, mechanical ventilation use, SOFA score, DM, sepsis, COPD, CHF, AMI, arrhythmia, pneumonia, serum potassium, and serum sodium levels were adjusted for. BMI, body mass index; SOFA, sequential organ failure assessment; COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure; AMI, acute myocardial infarction; DM, diabetes mellitus.

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Fig 4.

ROC curves comparing the predictive efficacy of the BUCR, Scr, and BUN for 28-day hospital mortality.

BUCR, BUN/serum creatinine; Scr, serum creatinine; BUN, Blood Urea Nitrogen.

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Fig 5.

Subgroup analysis of BUCR in predicting 28-day in-hospital mortality.

Age, gender, ethnicity, BMI, mechanical ventilation use, SOFA score, DM, sepsis, COPD, CHF, AMI, arrhythmia, pneumonia, serum potassium, and serum sodium levels were adjusted for. BMI, body mass index; SOFA, sequential organ failure assessment; COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure; AMI, acute myocardial infarction; DM, diabetes mellitus.

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Fig 6.

Association between BUCR and 28-day in-hospital mortality using multi-group propensity score weighting analysis.

Adjusted age, gender, ethnicity, BMI, mechanical ventilation use, SOFA score, DM, sepsis, COPD, CHF, AMI, arrhythmia, pneumonia, serum potassium, and serum sodium levels were adjusted for. BMI, body mass index; SOFA, sequential organ failure assessment; COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure; AMI, acute myocardial infarction; DM, diabetes mellitus.

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