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Fig 1.

Illustrates a SPIRIT Schedule of the study.

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Table 1.

Illustrates baseline data collected.

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Table 1 Expand

Table 2.

Illustrates overview of patient reported variables collected.

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Table 2 Expand

Table 3.

Illustrates data collection overview.

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Table 3 Expand

Fig 2.

Illustrates the study design and data collection points.

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Fig 2 Expand