Fig 1.
Flow chart of the FeToxCancer study design.
(in grey: phase II is ongoing and therefore not a part of this study; the map was produced using R programme (version 4.2.3) with Swedish county boundaries obtained from Eurostat’s GISCO database [23]).
Table 1.
National registries used to obtain data for the investigated perinatal characteristics.
Table 2.
Distribution of childhood cancer cases by year of birth, year of diagnosis, age at diagnosis, sex, and cancer type.
Table 3.
Distribution of studied perinatal characteristics between cases and controls within FeToxCancer study.
Table 4.
Associations of perinatal characteristics with the risk of overall childhood cancer.
Table 5.
Summarised associations of perinatal characteristics with the risk of leukaemia, CNS tumour, lymphoma and other cancer types combined (i.e., ICCC group IV-XII including unclassified diagnoses).
Fig 2.
Associations of birthweight for GA (a), mechanical ventilation treatment (b) and planned caesarean delivery (c) with the risk of overall childhood cancer, and other cancer types combined, stratified by age at diagnosis.
(*** p <0.001, ** p <0.01, * p <0.05; a– adjusted according to model 3, NA – not available due to low observation number (i.e., < 10); AGA – adequate for GA, SGA – small for GA, LGA – large for GA; other types combined – ICCC group IV-XII, including unclassified diagnoses).