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Fig 1.

Preparation Steps for LN@AgNPs (change of color from transparent to brown showed that nanoconjugation occurred).

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Fig 1 Expand

Fig 2.

Ultraviolet-visible spectroscopy: SPR bands spectrum of LN@AgNPs.

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Fig 2 Expand

Fig 3.

Particle size determination of synthesized nanoparticles.

(a) size distribution by intensity (b) size distribution histogram based on number data.

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Fig 3 Expand

Fig 4.

Zeta potential measurement: Analysis of zeta potential of synthesized silver nanoconjugates of Linalool.

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Fig 4 Expand

Fig 5.

FTIR spectrum of LN@AgNPs: Graph with wavelength (cm-1) on the x-axis and transmittance percentage on the y-axis.

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Fig 5 Expand

Fig 6.

SEM image of LN@AgNPs: Magnified image of selected area (left) with number of particles with respective area (right).

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Fig 6 Expand

Fig 7.

EDAX spectrum of LN@AgNPs.

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Fig 8.

Interaction diagram of ligands.

(a-b LN@AgNPs, c. Linalool) to binding site of Glyceraldehyde-3-phosphate dehydrogenase A (GAPDH) of E.coli (6IO4).

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Fig 9.

Interaction diagram of ligands.

(a. LN@AgNPs, b. Linalool) to binding site of FtsZ B. of Bacillus subtilis (2VAM) and ligands (c. LN@AgNPs, d. Linalool) to binding site of type IVb pilin from Salmonella enteric (3FHU).

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Table 1.

Molecular interaction Profile of LN@AgNPs and individual linalool with selected targets.

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Table 1 Expand

Fig 10.

A microtiter plate showing minimum inhibitory concentration (MIC): Score growth in test wells presence/absence of turbidity (1. Positive control, 2. Negative control, 3.Linalool and 4. LN@AgNPs) against Salmonella enterica, E.coli and Bacillus subtilis.

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Table 2.

Determination of MIC (μL/mL) and %Inhibition by microdilution method.

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Table 2 Expand

Fig 11.

Antibacterial activity evaluating using Agar-well diffusion method: micro plates for bacterial strains Salmonella enterica, E.coli and Bacillus subtilis with zone of inhibitions labeled with negative control (c), positive control (AZM), Linalool (LN) and LN@AgNPs (Left) and bar-graph showing zone of inhibitions (right).

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Fig 11 Expand

Fig 12.

Antibacterial activity evaluating using Disc diffusion method: micro plates for bacterial strains; Salmonella enterica, E.coli and Bacillus subtilis with zone of inhibitions labeled with negative control (c), positive control (AZM), Linalool (LN) and LN@AgNPs (Left) and bar-graph showing zone of inhibitions (right).

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Fig 12 Expand