Fig 1.
A 3.4-mm diameter cryoprobe, and a guide needle system consisting of a guide needle and inner and outer sheaths.
Fig 2.
(a) A tumor is visible in the dorsal segment of the left upper lobe (arrow). First, (b) guide needle system is used for the outer sheath to penetrate the tumor, then (c) the cryoprobe is introduced into the outer sheath, followed by cryoablation. (d) Follow-up computed tomography images 5 months after treatment.
Table 1.
Patient characteristics.
Fig 3.
In total, 78 of 220 patients with stage I non-small cell lung cancer tumors ≥2 cm underwent cryoablation, of which 64 were treated by SBRT followed by cryoablation. SBRT, stereotactic body radiation therapy.
Table 2.
SBRT and cryoablation treatment details.
Fig 4.
Kaplan–Meier curves for 3- and 5-years for (a) local control (both 93%); (b) overall survival (87% and 74%, respectively); (c) recurrence-free survival.
(74% and 60%, respectively); and (d) disease-specific survival (96% and 92%, respectively). The shaded area indicates the 95% confidence interval.
Table 3.
Cox proportional hazard regression analyses for overall survival.