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Fig 1.

Schematic illustration of the Swin UNETR architecture used for volumetric segmentation of the prostate CTV.

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Fig 2.

Training workflows for the PSN framework.

(a) PSNadaptive: the model is fine-tuned on cumulatively increasing fractions and tested on subsequent ones. (b) PSNsequence: the model is sequentially fine-tuned using the previously trained weights for each next fraction. DLg represents the pre-trained model, and n denotes the patient index (n = 1, 2,..., 5).

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Fig 2 Expand

Table 1.

Average DSC, HD, and MSD for the Deform from ETHOS, the pre-trained Swin UNETR model, and the PSNadaptive approach using Swin UNETR, along with their standard deviations, as illustrated in Fig 2(a).

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Table 2.

Average DSC, HD, and MSD for the PSNadaptive and the PSNsequence approach using Swin UNETR, along with their standard deviations, as illustrated in Fig 2.

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Table 2 Expand

Fig 3.

Average DSC, HD, and MSD values (± standard deviation) for prostate CTV segmentation.

Results are shown for the deformable registration method (ETHOS), pre-trained model (Swin UNETR), PSNadaptive (Fig 2(a)), and PSNsequence (Fig 2(b)).

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Fig 3 Expand

Table 3.

Absolute deviations from physician-defined CTV dose (|ΔD95|, |ΔD98|, |ΔDmean|, |ΔD2|) across fractions.

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Table 3 Expand

Fig 4.

(a–b) Visual comparisons of CTV segmentation against reference contours (red), including outputs from the deformed planning CT (yellow), pre-trained model (green), and PSNadaptive (blue).

(a) Axial slice; (b) magnified view in a complex region. (c–e) 3D deviation maps between reference contours and segmentation results from the pre-trained model (c), deformed CT (d), and PSNadaptive model trained on the 1st fraction (e).

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Fig 4 Expand