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Fig 1.

A schematic-diagram illustrating the production, characterisation, and applications of MgO-NPs synthesized by WP extract.

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Fig 2.

3D crystallography of the DHFR enzyme obtained from protein data bank.

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Fig 3.

UV-vis spectrum of biosynthesis MgONPs.

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Fig 4.

FT-IR spectra of biosynthesized MgONPs.

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Fig 5.

XRD analysis of biosynthesized MgONPs.

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Fig 6.

TEM image of the biosynthesized MgONPs.

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Fig 7.

Antimicrobial properties of MgONPs versus different microbial strains.

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Fig 8.

Antibiofilm activity of biosynthesized MgONPs toward MRSA at varying doses.

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Fig 9.

Light-inverted microscopy pictures of S. aureus biofilms cultivated in different MgONPs doses.

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Fig 10.

Structural interaction of MgO-NPs within the active site of dihydrofolate reductase (DHFR) (PDB ID: 2W9H).

(A & B) 3D representations showing the binding mode of MgO-NPs within the DHFR active site, highlighting interactions with surrounding amino acid residues. (C) 2D interaction diagram illustrating the binding of MgO-NPs within the active pocket and their interactions with key amino acids.

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Fig 11.

Antioxidant capability of biosynthesized MgONPs at varies concentrations.

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Fig 12.

Antiviral efficacy of bioـsynthesized MgONPs against HAV.

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Fig 13.

Antiviral efficacy of bioـsynthesized MgONPs against HSV1.

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