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Table 1.

Four grid table.

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Table 2.

ROR, PRR, BCPNN, and EBGM methods, formulas, and thresholds.

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Fig 1.

Flow chart.

The flow diagram of selecting spironolactone-related ADEs from FAERS database. Abbreviations: DEMO, demographic; REAC, Reporting Event Adverse Condition; PTs, Preferred Terms; PS, Primary Suspect; ROR, Reporting Odds Ratio; PRR, Proportional Reporting Ratio; BCPNN, Bayesian Confidence Propagation Neural Network; MGPS, multi-item gamma poisson shrinker.

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Fig 1 Expand

Table 3.

Basic information on ADEs related to spironolactone from the FAERS database.

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Table 3 Expand

Fig 2.

Year curve chart.

Curve plot of the adverse reaction reports for spironolactone over the years.

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Fig 2 Expand

Table 4.

The signal strength of ADEs of spironolactone at the SOC level in FAERS database.

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Table 4 Expand

Table 5.

The top 30 signal strength of adverse events of spironolactone ranked by ROR at the PTs level in FAERS database.

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Table 5 Expand