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Fig 1.

The population proportion sampling technique used in this study.

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Table 1.

Type of second-line ART regimen taken among PLHIV in selected Hospitals in Addis Ababa, Ethiopia, 2018-2022 (N = 369).

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Fig 2.

Second-line ART regimen change among PLHIV in Addis Ababa, Ethiopia.

(A) Second-line ART regimen change experience among enrolled patients in Addis Ababa, Ethiopia. (B) Reason for a second-line ART regimen change among PLHIV in Addis Ababa, Ethiopia.

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Fig 3.

Type of OI developed among PLHIV taking second-line ART in selected Hospitals in Addis Ababa, Ethiopia, 2018-2022.

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Table 2.

Multivariate Cox regression analysis of predictors of second-line ART failure of adult HIV-positive patients at selected hospitals in Addis Ababa, Ethiopia, 2018-2022, (n = 369).

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Fig 4.

Kaplan-Meier survival estimates.

(A) Overall Kaplan-Meier failure curve showing hazard from treatment failure of HIV-positive adults on second-line antiretroviral therapy at selected hospitals in Addis Ababa, Ethiopia, 2018-2022, (n = 369). (B) Kaplan-Meier failure curve with 95% CI for treatment failures in HIV-positive adults on second-line antiretroviral therapy in Addis Ababa, Ethiopia (2018-2022, n = 369).

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Table 3.

Cumulative probability of failure of adult Patients on second-line ART at selected hospitals in Addis Ababa, Ethiopia, 2018-2022.

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