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Fig 1.

Flowchart of patient inclusion.

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Fig 2.

Workflow diagram.

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Table 1.

Baseline characteristics of the patients.

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Table 2.

Comparison of ROC performance before and after optimization.

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Table 3.

Optimized model prediction performance.

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Fig 3.

Feature selection using the Boruta algorithm.

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Fig 4.

Receiver operating characteristic curves of 16 models for in-hospital mortality in patients with coronary heart disease with diabetes mellitus.

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Fig 5.

Permutation importance (a, c) and SHAP summary plots (b, d) for the Gradient Boosting Classifier and Random Forest Classifier, showing variable associations with in-hospital mortality.

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Fig 6.

The SHapley Additive exPlanations (SHAP) waterfall.

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