Table 1.
Primers list for PCR.
Table 2.
Demographic and clinical-pathological characteristics of patients with thyroid nodules.
Table 3.
Distribution of demographic, clinical, and ultrasound parameters according to mutation profile.
Fig 1.
Classification of thyroid nodules based on cytological analysis.
The diagram illustrates the classification of thyroid nodules according to their cytology based on the 2023 Bethesda system, the presence of mutations and the subsequent post-surgery histopathological results [5,19].
Fig 2.
Correlation between cytology, molecular findings, and histological diagnosis.
LT: lymphocytic thyroiditis; TFND: thyroid follicular nodular disease; FA: follicular adenoma; PTC: papillary thyroid cancer; IFV-PTC: infiltrative follicular variant papillary thyroid carcinoma; FTC: follicular thyroid cancer; FNA: fine-needle aspiration; NIFTP: non-invasive follicular thyroid neoplasm with papillary-like nuclear features [5,19].
Table 4.
Probability of cancer in thyroid nodules depending on the results of cytological and molecular analysis.
Fig 3.
Performance of molecular testing in specific categories of indeterminate FNA cytology.
NIFTP (Noninvasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features) was considered a malignant neoplasm [5,19].