Table 1.
Description of features.
Fig 1.
Overview of the study pipeline.
Abbreviations: GCN, graph convolutional network.
Fig 2.
Pairwise correlation heatmaps of the 51 correlated features in five groups (HRV features, vital signs features, pathology test results, injury scores (GCS) and demographics).
Abbreviations: SDNN, standard deviation of RR; SDANN, standard deviation of the average RR; MeanRR, mean value of RR; RMSSD, square root of mean squared differences of RR; pNN50, number of interval differences of successive RRI intervals >50 ms divided by the total RRI’s; P_VLF, Power in very low-frequency range; P_LF, Power in the low-frequency range; P_HF, Power in the high-frequency range; HF/LF, Ratio HF/LF; REC, percentage of recurrent points; DET, ratio of the length of diagonal lines; LAM, ratio of vertical lines (recurrence plot); SD1, Short term variability; SD2, Long term variability; Alpha1 and Alpha2- correlation within the signal (Detrended fluctuations); HR, heart rate; DBP, diastolic blood pressure; SBP, systolic blood pressure; ABPM, arterial blood pressure mean; SpO2, peripheral oxygen saturation; SO2, oxygen saturation level; PO2, partial pressure of oxygen saturation; PCO2, partial pressure of carbon dioxide level; GCS(eyes)_12hr, Glasgow coma scale eye response after 12 hours from admission; GCS(motor)_12hr, Glasgow coma scale motor response after 12 hours from admission; GCS_12hr (verbal), Glasgow coma scale verbal response after 12 hours from admission; GCS_final, final recorded total value of Glasgow coma scale.
Fig 3.
Relationship between physiological/clinical features (a) Witcher Network: Relationship between features and the correlation threshold was 0.5.
(b) Relationship between the feature groups. Abbreviations: SDNN, standard deviation of RR; SDANN, standard deviation of the average RR; MeanRR, mean value of RR; RMSSD, square root of mean squared differences of RR; pNN50, number of interval differences of successive RRI intervals >50 ms divided by the total RRI’s; P_VLF, Power in very low-frequency range; P_LF, Power in the low-frequency range; P_HF, Power in the high-frequency range; HF/LF, Ratio HF/LF; REC, percentage of recurrent points; DET, ratio of the length of diagonal lines; LAM, ratio of vertical lines (recurrence plot); SD1, Short term variability; SD2, Long term variability; Alpha1 and Alpha2- correlation within the signal (Detrended fluctuations); HR, heart rate; DBP, diastolic blood pressure; SBP, systolic blood pressure; ABPM, arterial blood pressure mean; SpO2, peripheral oxygen saturation; SO2, oxygen saturation level; PO2, partial pressure of oxygen saturation; PCO2, partial pressure of carbon dioxide level; GCS(eyes)_12hr, Glasgow coma scale eye response after 12 hours from admission; GCS(motor)_12hr, Glasgow coma scale motor response after 12 hours from admission; GCS_12hr (verbal), Glasgow coma scale verbal response after 12 hours from admission; GCS_final, final recorded total value of Glasgow coma scale.
Fig 4.
Twenty features with the highest significance scores from GCN analysis.
Abbreviations: SDNN, standard deviation of RR; MeanRR, mean value of RR; pNN50, number of interval differences of successive RRI intervals >50 ms divided by the total RRI’s; P_VLF, Power in very low-frequency range; SD1, Short term variability; SD2, Long term variability; HR, heart rate; DBP, diastolic blood pressure; SBP, systolic blood pressure; ABPM, arterial blood pressure mean; SpO2, peripheral oxygen saturation; SO2, oxygen saturation level; PO2, partial pressure of oxygen saturation; GCS(eyes)_12hr, Glasgow coma scale eye response after 12 hours from admission; GCS(motor)_12hr, Glasgow coma scale motor response after 12 hours from admission; GCS_12hr (verbal), Glasgow coma scale verbal response after 12 hours from admission.