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Fig 1.

Intraoperative findings of the intersegmental plane description using the I-D method and ICG-iv method.

(A) I-D method. (B) ICG-iv method.

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Fig 2.

Calculation of margins.

(A) The planned margins were calculated using Ziostation (Ziosoft, Tokyo, Japan) based on CT data. (B) The surgical margins were measured as the distance between the tumor rim and the resection edge in the resected specimen.

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Table 1.

Preoperative and perioperative patient characteristics (n = 138).

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Table 2.

Surgical and pathological characteristics (n = 140).

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Table 3.

Comparison of the accuracy of intersegmental plane identification using the Inflation-deflation method or indocyanine green intravenous administration method (n = 140).

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Fig 3.

Logarithmic transformation of S/P ratio.

The mean log S/P ratios were −0.061 (95% confidence interval: −0.118 to −0.004) in the I-D group and −0.013 (95% confidence interval: −0.082 to 0.056) in the ICG-iv group. ICG-iv, Indocyanine green intravenous administration; I-D, Inflation-deflation; S/P ratio, Surgical and planned margin ratio.

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Fig 4.

Relationships between the surgical margin and the distance of STAS from the primary tumor among the lesions with STAS.

(A) I-D group (n = 11). The median surgical margin was 16 mm (6–77), and the median distance of the STAS from the primary tumor was 3 mm (1–7), showing a significant difference (P < 0.001). (B) ICG-iv group (n = 8). The median surgical margin was 19 mm (11–30), and the median distance of the STAS from the primary tumor was 1 mm (1–8), showing a significant difference (P < 0.001). ICG-iv, Indocyanine green intravenous administration; I-D, Inflation-deflation; STAS, Spread through air spaces.

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Fig 4 Expand

Table 4.

Comparison of patient and surgical characteristics between good staining and poor staining group in the intersegmental plane with intravenous indocyanine green administration (n = 52).

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