Table 1.
All-age cases and age-standardized incidence, prevalence, deaths, DALYs, YLDs, and YLLs rates in 2021 for pancreatic cancer in China.
Fig 1.
Age and sex distribution of deaths, prevalence, and incidence rates of pancreatic cancer in China in 2021. (A) Age-specific and gender-specific number of incident cases of pancreatic cancer. (B) Age-specific and gender-specific rate of incidence of pancreatic cancer per 100,000 people. (C) Age-specific and gender-specific number of prevalent cases of pancreatic cancer. (D) Age-specific and gender-specific rate of prevalence of pancreatic cancer per 100,000 people. (E) Age-specific and gender-specific number of pancreatic cancer deaths. (F) Age-specific and gender-specific rate of deaths due to pancreatic cancer per 100,000 people.
Fig 2.
Temporal trends in the incidence, prevalence, deaths, DALYs, YLDs, and YLLs of pancreatic cancer in China from 1990 to 2021, by sex.
(A) The number of incident cases and age-standardized incidence rates per 100,000 people from 1990 to 2021. (B) The number of prevalent cases and age-standardized prevalence rates per 100,000 people from 1990 to 2021. (C) The number of deaths and age-standardized mortality rates per 100,000 people from 1990 to 2021. (D) The number of DALYs and age-standardized DALY rates per 100,000 people from 1990 to 2021. (E) The number of YLDs and age-standardized YLD rates per 100,000 people from 1990 to 2021. (F) The number of YLLs and age-standardized YLL rates per 100,000 people from 1990 to 2021. Abbreviations: DALYs, disability-adjusted life years; YLDs, years lived with disability; YLLs, years of life lost.
Table 2.
Change of age-standardized rates in incidence, prevalence, deaths, DALYs, YLDs, and YLLs for pancreatic cancer between 1990 and 2021 in China and global level.
Fig 3.
Joinpoint regression analysis of age-standardized rates for pancreatic cancer in China from 1990 to 2021.
(A) Age-standardized incidence rates for males (gray line) and females (green line), with the overall population trend represented by the blue line, showing intervals of significant increases. (B) Age-standardized prevalence rates for males, females, and the overall population, illustrating prevalence trends over time. (C) Age-standardized mortality rates for males and females, along with the total population trend, indicating key periods of increase in mortality rates. (D) DALYs for pancreatic cancer, capturing the combined burden across both sexes and the overall population. (E) YLDs for males and females, compared to the overall population, indicating the non-fatal burden over time. (F) YLLs metrics for both sexes, depicting the fatal burden of pancreatic cancer across the population. Abbreviations: DALYs, disability-adjusted life years; YLDs, years lived with disability; YLLs, years of life lost.
Fig 4.
Age, period, and cohort effects on the incidence of pancreatic cancer in China.
(A) Age-standardized incidence rates of pancreatic cancer according to time periods; each line connects the age-specific incidence for a 5-year period. (B) Age-standardized incidence rates of pancreatic cancer according to birth cohorts; each line connects the age-specific incidence for a 5-year birth cohort. (C) Period-specific incidence rates of pancreatic cancer according to age groups; each line connects the period-specific incidence for a 5-year age group. (D) Cohort-specific incidence rates of pancreatic cancer according to age groups; each line connects the cohort-specific incidence for a 5-year age group.
Fig 5.
Decomposition analysis of the changes in incidence, prevalence, and DALYs of pancreatic cancer in China, by sex.
The contributions of each factor to the total increase are depicted. (A) Decomposition of the increase in pancreatic cancer incidence into aging, epidemiological change, and population growth for both sexes, males, and females. (B) Decomposition of the increase in pancreatic cancer prevalence into aging, epidemiological change, and population growth for both sexes, males, and females. (C) Decomposition of the increase in pancreatic cancer DALYs into aging, epidemiological change, and population growth for both sexes, males, and females.
Fig 6.
BAPC analysis of pancreatic cancer incidence, prevalence and DALYs in China by sex.
(A) BAPC model projections of age-specific pancreatic cancer incidence rates for females. (B) BAPC model projections of age-specific pancreatic cancer incidence rates for males. (C) BAPC model projections of age-specific pancreatic cancer prevalence rates for females. (D) BAPC model projections of age-specific pancreatic cancer prevalence rates for males. (E) BAPC model projections of age-specific pancreatic cancer DALYs rates for females. (F) The projections show the expected trends in DALYs rates across different age groups over time. BAPC, Bayesian age-period-cohort; DALYs, disability-adjusted life years.