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Table 1.

Pathogenic variants and variants of uncertain significance (VUS) identified in the CS patients.

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Table 2.

Pathogenic and variants of uncertain significance (VUS) identified in unaffected relatives.

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Table 3.

EnrichR analysis.

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Fig 1.

Results of STRING analysis for 15 genes with VUS specific to CS patients.

Nodes (= query proteins) are represented by coloured circles; filled nodes indicate that the protein structure is known or predicted. Protein-protein interactions are represented by coloured lines as indicated in the key. These interactions indicated that proteins contribute to a shared function but does not necessarily mean they are physically binding each other (https://string-db.org/).

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